Daye Cheng1, Hong Kong, Yunhui Li. 1. Department of Transfusion, The First Hospital of China Medical University, Shenyang, Liaoning Province, PR China. dayecheng_cmu@yahoo.cn
Abstract
OBJECTIVE: The aim of this study was to evaluate the prognostic value of VEGF and IL-8 in pleural effusion in patients with lung cancer. MATERIALS AND METHOD: Commercially available ELISA was used to determine VEGF and IL-8 levels. RESULTS: The level of VEGF showed significant correlations with lymph node metastasis and distant metastasis. But, IL-8 was only correlated with lymph node metastasis. Univariate and multivariate analysis revealed elevated VEGF level was an independent predictor of shorter OS and DFS. CONCLUSION: VEGF could be an important component that contributes to pleural effusion formation, and an important prognostic factor for lung cancer.
OBJECTIVE: The aim of this study was to evaluate the prognostic value of VEGF and IL-8 in pleural effusion in patients with lung cancer. MATERIALS AND METHOD: Commercially available ELISA was used to determine VEGF and IL-8 levels. RESULTS: The level of VEGF showed significant correlations with lymph node metastasis and distant metastasis. But, IL-8 was only correlated with lymph node metastasis. Univariate and multivariate analysis revealed elevated VEGF level was an independent predictor of shorter OS and DFS. CONCLUSION:VEGF could be an important component that contributes to pleural effusion formation, and an important prognostic factor for lung cancer.
Authors: Michał Sobjanek; Monika Zabłotna; Aleksandra Lesiak; Igor Michajłowski; Aneta Szczerkowska-Dobosz; Małgorzata Sokolowska-Wojdylo; Roman Nowicki Journal: Arch Dermatol Res Date: 2014-06-06 Impact factor: 3.017
Authors: Murali M S Balla; Sejal Desai; Pallavi Purwar; Amit Kumar; Prashant Bhandarkar; Yogesh K Shejul; C S Pramesh; S Laskar; Badri N Pandey Journal: Sci Rep Date: 2016-11-04 Impact factor: 4.379