Literature DB >> 23684997

Taiwan food scandal: the illegal use of phthalates as a clouding agent and their contribution to maternal exposure.

Justin Yang1, Russ Hauser, Rose Hannah Goldman.   

Abstract

In 2011 the Taiwan Food and Drug Administration reported that plasticizers di(2-ethylhexyl) phthalate (DEHP) and di-iso-nonyl phthalate (DiNP), endocrine disruptors, were illegally added to clouding agents used in foods and beverages. 965 products were found contaminated, of which 206 were exported to 22 countries. This study's purpose was to obtain English names for 28 contaminated products for which DEHP levels were reported, calculate estimated average daily intake (mg/kg/day) for a 50 kg woman consuming one portion, and compare to U.S. and E.U. guidelines for daily intake. We found that drinking just one bottle (500 ml) of sports drinks would result in an average DEHP intake of 0.14 mg/kg bw/day (range 0.091-0.341), which exceeds by several fold government guidelines (0.02-0.06 mg/kg bw/day). One (2 g) serving from 4/14 samples of contaminated dietary supplements exceeds the guideline of 0.02 mg/kg bw/day. In conclusion, consuming even one portion of tainted drinks and some powders would lead to daily intake of DEHP that greatly exceeds established safety guidelines, raising concerns about potential adverse effects, particularly reproductive tract development in the male fetus. Global distribution of DEHP-contaminated and other adulterated products should prompt governments to become proactive in food safety regulations and chemical testing.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  AGD; ATSDR; Agency for Toxic Substances and Disease Registry; CADIA; CSTEE; China Alcoholic Drinks Industry Association; Clouding agent; DEHP; Di(2-ethylhexyl) phthalate (DEHP); DiNP; ECB/EU; Endocrine disruptor; European Chemicals Bureau; FSMA; Food Safety Modernization Act; Food contamination; MRL; Maternal exposure; PVC; Phthalate; RfD; Scientific Committee on Toxicity, Ecotoxicity and the Environment; TBIA; TDI; TFDA; Taiwan Beverage Industries Association; Taiwan Food and Drug Administration; US Environmental Protection Agency; US-EPA; anogenital distance; di(2-ethylhexyl) phthalate; di-iso-nonyl phthalate; minimal risk level; parts per million; polyvinyl chloride; ppm; reference dose; tolerable daily intake

Mesh:

Substances:

Year:  2013        PMID: 23684997     DOI: 10.1016/j.fct.2013.05.010

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  11 in total

1.  Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system.

Authors:  Qiang Ma; Hua Bai; Wentao Li; Chao Wang; Xinshi Li; R Graham Cooks; Zheng Ouyang
Journal:  Anal Chim Acta       Date:  2016-01-27       Impact factor: 6.558

2.  Is there any association between phthalate exposure and precocious puberty in girls?

Authors:  Mahin Hashemipour; Roya Kelishadi; Mohammad Mehdi Amin; Karim Ebrahim
Journal:  Environ Sci Pollut Res Int       Date:  2018-03-01       Impact factor: 4.223

3.  Leaching of phthalate esters from different drinking stuffs and their subsequent biodegradation.

Authors:  Muhammad Ali Surhio; Farah N Talpur; Shafi M Nizamani; Marvi Kanwal Talpur; Hassan Imran Afridi; Abid Ali Khaskheli; Shazia Bhurgri; Junaid Ali Surhio
Journal:  Environ Sci Pollut Res Int       Date:  2017-06-25       Impact factor: 4.223

4.  Exposure Estimation for Risk Assessment of the Phthalate Incident in Taiwan.

Authors:  Chu-Chih Chen; Shu-Li Wang; Ming-Tsang Wu; Yin-Han Wang; Po-Chin Huang; Bai-Hsiun Chen; Chien-Wen Sun; Chi-Kung Ho; Yang-Chih Shih; Ming-Neng Shiu; Wen-Harn Pan; Mei-Lien Chen; Ching-Chang Lee; Chao A Hsiung
Journal:  PLoS One       Date:  2016-03-09       Impact factor: 3.240

5.  Changes in Urinary Phthalate Metabolite Levels Before and After the Phthalate Contamination Event and Identification of Exposure Sources in a Cohort of Taiwanese Children.

Authors:  Chian-Feng Huang; I-Jen Wang
Journal:  Int J Environ Res Public Health       Date:  2017-08-19       Impact factor: 3.390

6.  Optimization of Sample Preparation for Detection of 10 Phthalates in Non-Alcoholic Beverages in Northern Vietnam.

Authors:  Thanh-Thien Tran-Lam; Yen Hai Dao; Duong Thanh Nguyen; Hoi Kim Ma; Trung Quoc Pham; Giang Truong Le
Journal:  Toxics       Date:  2018-11-19

7.  Association between Urinary Phthalate Metabolites and Markers of Endothelial Dysfunction in Adolescents and Young Adults.

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Journal:  Toxics       Date:  2021-02-06

8.  Prenatal Exposures to Common Phthalates and Prevalent Phthalate Alternatives and Infant DNA Methylation at Birth.

Authors:  Rebekah L Petroff; Vasantha Padmanabhan; Dana C Dolinoy; Deborah J Watkins; Joseph Ciarelli; Diana Haggerty; Douglas M Ruden; Jaclyn M Goodrich
Journal:  Front Genet       Date:  2022-03-31       Impact factor: 4.772

9.  Phthalate Exposure Pattern in Breast Milk within a Six-Month Postpartum Time in Southern Taiwan.

Authors:  Shen-Che Hung; Ting-I Lin; Jau-Ling Suen; Hsien-Kuan Liu; Pei-Ling Wu; Chien-Yi Wu; Yu-Chen S H Yang; San-Nan Yang; Yung-Ning Yang
Journal:  Int J Environ Res Public Health       Date:  2021-05-26       Impact factor: 3.390

10.  Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis.

Authors:  Xiaolin Li; Evandro Fei Fang; Morten Scheibye-Knudsen; Honghua Cui; Lu Qiu; Jian Li; Yuping He; Jing Huang; Vilhelm A Bohr; Tzi Bun Ng; Hongwei Guo
Journal:  Sci Rep       Date:  2014-09-22       Impact factor: 4.379

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