AIM: The aim of this study was to assess the hypothesis that patients with Parkinson's disease (PD) may have difficulties in tasks of affective theory of mind (ToM; the inference on others' feelings) especially in moderate/advanced PD stages. Difficulties of cognitive ToM have already been described in several previous studies. METHODS: Affective ToM was assessed with the Reading the Mind in the Eyes task in 35 PD patients and 35 healthy controls. Depression, global cognitive status and executive functioning were also evaluated. Patients were distinguished in early PD and moderate PD according to their scores in the Hoehn and Yahr Staging Scale. RESULTS: PD patients had more difficulties with affective ToM than healthy controls, also controlling for other variables that resulted in association with this ability. Early PD patients outperformed moderate PD patients, but this difference did not reach statistical significance when controlling for other variables. CONCLUSION: These findings confirmed that affective ToM may be impaired in PD, but any conclusion can be made on the effect of disease progression on this ability of social cognition. Therefore, longitudinal studies are needed to investigate this potential effect.
AIM: The aim of this study was to assess the hypothesis that patients with Parkinson's disease (PD) may have difficulties in tasks of affective theory of mind (ToM; the inference on others' feelings) especially in moderate/advanced PD stages. Difficulties of cognitive ToM have already been described in several previous studies. METHODS: Affective ToM was assessed with the Reading the Mind in the Eyes task in 35 PDpatients and 35 healthy controls. Depression, global cognitive status and executive functioning were also evaluated. Patients were distinguished in early PD and moderate PD according to their scores in the Hoehn and Yahr Staging Scale. RESULTS:PDpatients had more difficulties with affective ToM than healthy controls, also controlling for other variables that resulted in association with this ability. Early PDpatients outperformed moderate PDpatients, but this difference did not reach statistical significance when controlling for other variables. CONCLUSION: These findings confirmed that affective ToM may be impaired in PD, but any conclusion can be made on the effect of disease progression on this ability of social cognition. Therefore, longitudinal studies are needed to investigate this potential effect.
Authors: Jonathan M Grabyan; Erin E Morgan; Marizela V Cameron; Javier Villalobos; Igor Grant; Steven Paul Woods Journal: Arch Clin Neuropsychol Date: 2018-03-01 Impact factor: 2.813
Authors: Lindsey G McIntosh; Sishir Mannava; Corrie R Camalier; Bradley S Folley; Aaron Albritton; Peter E Konrad; David Charles; Sohee Park; Joseph S Neimat Journal: Front Aging Neurosci Date: 2015-01-21 Impact factor: 5.750
Authors: Matthias L Schroeter; Sarah Pawelke; Sandrine Bisenius; Jana Kynast; Katharina Schuemberg; Maryna Polyakova; Sarah Anderl-Straub; Adrian Danek; Klaus Fassbender; Holger Jahn; Frank Jessen; Johannes Kornhuber; Martin Lauer; Johannes Prudlo; Anja Schneider; Ingo Uttner; Angelika Thöne-Otto; Markus Otto; Janine Diehl-Schmid Journal: Front Aging Neurosci Date: 2018-01-30 Impact factor: 5.750