Literature DB >> 23682739

The paradox of overnutrition in aging and cognition.

Roger A Fielding1, John Gunstad, Deborah R Gustafson, Steven B Heymsfield, John G Kral, Lenore J Launer, Josef Penninger, David I W Phillips, Nikolaos Scarmeas.   

Abstract

Populations of many countries are becoming increasingly overweight and obese, driven largely by excessive calorie intake and reduced physical activity; greater body mass is accompanied by epidemic levels of comorbid metabolic diseases. At the same time, individuals are living longer. The combination of aging and the increased prevalence of metabolic disease is associated with increases in aging-related comorbid diseases such as Alzheimer's disease, cerebrovascular dementia, and sarcopenia. Here, correlative and causal links between diseases of overnutrition and diseases of aging and cognition are explored.
© 2013 New York Academy of Sciences.

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Year:  2013        PMID: 23682739      PMCID: PMC5166614          DOI: 10.1111/nyas.12138

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  48 in total

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5.  An elaborative NMR based plasma metabolomics study revealed metabolic derangements in patients with mild cognitive impairment: a study on north Indian population.

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  8 in total

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