Literature DB >> 23682615

The changes in the hair cycle during gestation and the post-partum period.

S Gizlenti1, T R Ekmekci.   

Abstract

BACKGROUND: In pregnancy, increased numbers of hair follicles remain in the anagen phase for longer periods due to hormonal changes and return to the telogen phase within 3-6 months of delivery with a sudden drop in hormone levels. This results in excessive shedding of hair known as post-partum telogen effluvium.
OBJECTIVE: To determine the changes in the hair cycle during gestation and the post-partum period.
METHODS: We included 116 women in this study; 28 women at the 24th week of pregnancy, 30 pregnant women at term gestation, 29 women in the 4th post-partum month, and 29 in the first post-partum year. The number of breastfeeding mothers in the post-partum period and the month in which they were examined were also recorded. The ratios of anagen and telogen were measured using Trichoscan.
RESULTS: A statistically significant difference was observed between the groups in terms of the anagen and telogen ratios (P = 0.042, P = 0.042). In the inter-group comparisons, the mean anagen rate in the 4th post-partum month was significantly lower than that in the 6th and 9th month of pregnancy (P = 0.045, P = 0.038), while the average telogen rate was significantly higher (P = 0.045, P = 0.038). The mean anagen rate in the 4th post-partum month in the breastfeeding group was significantly higher than that in the non- breastfeeding group (P = 0.014), while the mean telogen rate was significantly lower (P = 0.014). There was no statistically significant difference between the two groups (the breastfeeding and non-breastfeeding groups) in terms of the mean anagen and mean telogen ratios in the first post-partum year (P = 0.385).
CONCLUSION: The anagen rate increases during pregnancy and the telogen rate rises after delivery, however, there is no exaggeration in these changes in most women.
© 2013 The Authors Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of the European Academy of Dermatology and Venereology.

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Year:  2013        PMID: 23682615     DOI: 10.1111/jdv.12188

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  10 in total

Review 1.  The Postpartum Telogen Effluvium Fallacy.

Authors:  Oriol Mirallas; Ramon Grimalt
Journal:  Skin Appendage Disord       Date:  2016-04-20

2.  Transgenic flash mice for in vivo quantitative monitoring of canonical Wnt signaling to track hair follicle cycle dynamics.

Authors:  Samantha S Hodgson; Zoltan Neufeld; Rehan M Villani; Edwige Roy; Kiarash Khosrotehrani
Journal:  J Invest Dermatol       Date:  2014-02-14       Impact factor: 8.551

3.  Stress-associated ectopic differentiation of melanocyte stem cells and ORS amelanotic melanocytes in an ex vivo human hair follicle model.

Authors:  Inbal Rachmin; Ju Hee Lee; Bing Zhang; James Sefton; Inhee Jung; Young In Lee; Ya-Chieh Hsu; David E Fisher
Journal:  Exp Dermatol       Date:  2021-03-03       Impact factor: 3.960

4.  Blood and hair manganese concentrations in pregnant women from the infants' environmental health study (ISA) in Costa Rica.

Authors:  Ana M Mora; Berna van Wendel de Joode; Donna Mergler; Leonel Córdoba; Camilo Cano; Rosario Quesada; Donald R Smith; José A Menezes-Filho; Thomas Lundh; Christian H Lindh; Asa Bradman; Brenda Eskenazi
Journal:  Environ Sci Technol       Date:  2014-03-06       Impact factor: 9.028

Review 5.  Physiologic changes of pregnancy: A review of the literature.

Authors:  Catherine C Motosko; Amy Kalowitz Bieber; Miriam Keltz Pomeranz; Jennifer A Stein; Kathryn J Martires
Journal:  Int J Womens Dermatol       Date:  2017-10-21

6.  Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium.

Authors:  Shane A Grace; Angela M Sutton; Nina Abraham; Eric S Armbrecht; Claudia I Vidal
Journal:  Int J Trichology       Date:  2017 Jan-Mar

7.  Pattern of skin diseases in a university hospital in Jeddah, Saudi Arabia: age and sex distribution.

Authors:  Hussein M Alshamrani; Mohammed A Alsolami; Abdulaziz M Alshehri; Anas K Salman; Mamdouh W Alharbi; Aseel J Alzuhayri; Nouf T Mleeh
Journal:  Ann Saudi Med       Date:  2019 Jan-Feb       Impact factor: 1.526

Review 8.  Telogen effluvium: a comprehensive review.

Authors:  Alfredo Rebora
Journal:  Clin Cosmet Investig Dermatol       Date:  2019-08-21

9.  Investigation of grape sap on wingless/integrated and β-catenin genes expression with histological factors on the hair follicle in rat.

Authors:  Mohammad Kazemi; Mohammad-Mohsen Taghavi; Ahmad Shabanizadeh; Zahra Taghipour; Ayat Kaeidi; Mahdi Shariati-Kohbanani
Journal:  Res Pharm Sci       Date:  2020-08-28

10.  Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation.

Authors:  Jill Goldstein; Sean Fletcher; Eve Roth; Christine Wu; Andrew Chun; Valerie Horsley
Journal:  Genes Dev       Date:  2014-04-14       Impact factor: 11.361

  10 in total

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