Literature DB >> 23682366

Raynaud phenomenon of the nipple in breastfeeding mothers: an underdiagnosed cause of nipple pain.

Meagan E Barrett1, Misha M Heller, Honor Fullerton Stone, Jenny E Murase.   

Abstract

OBJECTIVE: To elucidate the diagnostic criteria of Raynaud phenomenon of the nipple that will aid in recognizing and treating Raynaud phenomenon in breast feeding mothers with chronic deep nipple pain during lactation.
DESIGN: Retrospective review of a patient database composed of 22 cases of breastfeeding mothers who fit the diagnostic criteria for Raynaud phenomenon of the nipple.
SETTING: Menlo Dermatology Medical Group in Menlo Park, California, an academic-affiliated, private dermatologic referral center. PATIENTS: All patients diagnosed as having Raynaud phenomenon of the nipple evaluated from January 1, 2004,through December 31, 2010. MAIN OUTCOME MEASURES: The rate of failed treatment for Candida mastitis, the rate of improvement of symptoms with nifedipine use, and the overall rate of improvement of symptoms with appropriate therapy involving treatment of Raynaud phenomenon.
RESULTS: Among the 22 patients with Raynaud phenomenon of the nipple, previous treatment for Candida mastitis with oral or topical antifungals was ineffective in 20(91%). Of the 12 patients who tolerated a trial of nifedipine,10 (83%) reported decreased or resolved nipple pain. All patients experienced marked improvement of symptoms with appropriate therapy involving treatment of Raynaud phenomenon.
CONCLUSIONS: Most patients were treated with antifungals before presentation without resolution of nipple pain. Nifedipine appears to be an effective medication for the treatment of Raynaud phenomenon of the nipple. With appropriate management of Raynaud phenomenon,breastfeeding mothers demonstrated improvement of nipple pain. Raynaud phenomenon of the nipple should be considered in the differential diagnosis of nipple pain during lactation.

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Year:  2013        PMID: 23682366     DOI: 10.1001/jamadermatol.2013.1560

Source DB:  PubMed          Journal:  JAMA Dermatol        ISSN: 2168-6068            Impact factor:   10.282


  5 in total

1.  Role of oral antibiotics in treatment of breastfeeding women with chronic breast pain who fail conservative therapy.

Authors:  Ann M Witt; Kelly Burgess; Thomas R Hawn; Steven Zyzanski
Journal:  Breastfeed Med       Date:  2014-01-04       Impact factor: 1.817

2.  Raynaud's Phenomenon in the Breast Nipple Area.

Authors:  Beate Koschinski-Möller
Journal:  Dtsch Arztebl Int       Date:  2021-09-06       Impact factor: 5.594

Review 3.  Raynaud's Phenomenon: Reviewing the Pathophysiology and Management Strategies.

Authors:  Iqra Nawaz; Yashfa Nawaz; Eisha Nawaz; Muhammad Romail Manan; Adil Mahmood
Journal:  Cureus       Date:  2022-01-28

Review 4.  Nipple candidiasis and painful lactation: an updated overview.

Authors:  Kerasia-Maria Plachouri; Francesk Mulita; Chrysa Oikonomou; Margarita Papadopoulou; Ioanna Akrida; Eleftheria Vryzaki; Georgios-Ioannis Verras; Sophia Georgiou
Journal:  Postepy Dermatol Alergol       Date:  2022-05-31       Impact factor: 1.664

5.  Analysis of questions about use of drugs in breastfeeding to Norwegian drug information centres.

Authors:  Jan Anker Jahnsen; Sofia Frost Widnes; Jan Schjøtt
Journal:  Int Breastfeed J       Date:  2018-01-09       Impact factor: 3.461

  5 in total

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