Literature DB >> 23682242

Primary Sclerosing Cholangitis: Current and Future Management Strategies.

John E Eaton1, Jayant A Talwalkar.   

Abstract

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.

Entities:  

Keywords:  Diagnosis; Management; Primary sclerosing cholangitis

Year:  2013        PMID: 23682242      PMCID: PMC3652489          DOI: 10.1007/s11901-012-0155-1

Source DB:  PubMed          Journal:  Curr Hepat Rep        ISSN: 1540-3416


  95 in total

1.  Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC.

Authors:  Christophe Corpechot; Ahmed El Naggar; Armelle Poujol-Robert; Marianne Ziol; Dominique Wendum; Olivier Chazouillères; Victor de Lédinghen; Daniel Dhumeaux; Patrick Marcellin; Michel Beaugrand; Raoul Poupon
Journal:  Hepatology       Date:  2006-05       Impact factor: 17.425

2.  Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis.

Authors:  Tim O Lankisch; Jochen Metzger; Ahmed A Negm; Katja Vosskuhl; Eric Schiffer; Justyna Siwy; Tobias J Weismüller; Andrea S Schneider; Kathrin Thedieck; Ralf Baumeister; Petra Zürbig; Eva M Weissinger; Michael P Manns; Harald Mischak; Jochen Wedemeyer
Journal:  Hepatology       Date:  2011-01-03       Impact factor: 17.425

3.  Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.

Authors:  Laurent Castéra; Julien Vergniol; Juliette Foucher; Brigitte Le Bail; Elise Chanteloup; Maud Haaser; Monique Darriet; Patrice Couzigou; Victor De Lédinghen
Journal:  Gastroenterology       Date:  2005-02       Impact factor: 22.682

4.  Hepatic and extrahepatic malignancies in primary sclerosing cholangitis.

Authors:  Annika Bergquist; Anders Ekbom; Rolf Olsson; Dan Kornfeldt; Lars Lööf; Ake Danielsson; Rolf Hultcrantz; Stefan Lindgren; Hanne Prytz; Hanna Sandberg-Gertzén; Sven Almer; Fredrik Granath; Ulrika Broomé
Journal:  J Hepatol       Date:  2002-03       Impact factor: 25.083

5.  Increased prevalence of CFTR mutations and variants and decreased chloride secretion in primary sclerosing cholangitis.

Authors:  Sunil Sheth; Julie C Shea; Michele D Bishop; Sanjiv Chopra; Meredith M Regan; Emily Malmberg; Carolyn Walker; Ryan Ricci; Lap-Chee Tsui; Peter R Durie; Julian Zielenski; Steven D Freedman
Journal:  Hum Genet       Date:  2003-06-03       Impact factor: 4.132

6.  Improved survival with primary sclerosing cholangitis. A review of clinicopathologic features and comparison of symptomatic and asymptomatic patients.

Authors:  J H Helzberg; J M Petersen; J L Boyer
Journal:  Gastroenterology       Date:  1987-06       Impact factor: 22.682

7.  High prevalence of small duct primary sclerosing cholangitis among patients with overlapping autoimmune hepatitis and primary sclerosing cholangitis.

Authors:  Rolf Olsson; Hans Glaumann; Sven Almer; Ulrika Broomé; Barbro Lebrun; Annika Bergquist; Einar Björnsson; Hanne Prytz; Ake Danielsson; Stefan Lindgren
Journal:  Eur J Intern Med       Date:  2008-10-11       Impact factor: 4.487

8.  High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis.

Authors:  Keith D Lindor; Kris V Kowdley; Velimir A C Luketic; M Edwyn Harrison; Timothy McCashland; Alex S Befeler; Denise Harnois; Roberta Jorgensen; Jan Petz; Jill Keach; Jody Mooney; Carol Sargeant; Julie Braaten; Tamara Bernard; Debra King; Ellen Miceli; Jeff Schmoll; Tanya Hoskin; Prabin Thapa; Felicity Enders
Journal:  Hepatology       Date:  2009-09       Impact factor: 17.425

9.  Prevalence and risk factors for gallbladder neoplasia in patients with primary sclerosing cholangitis: evidence for a metaplasia-dysplasia-carcinoma sequence.

Authors:  Jason T Lewis; Jayant A Talwalkar; Charles B Rosen; Thomas C Smyrk; Susan C Abraham
Journal:  Am J Surg Pathol       Date:  2007-06       Impact factor: 6.394

10.  A re-evaluation of the risk factors for the recurrence of primary sclerosing cholangitis in liver allografts.

Authors:  Edward Alabraba; Peter Nightingale; Bridget Gunson; Stefan Hubscher; Simon Olliff; Darius Mirza; James Neuberger
Journal:  Liver Transpl       Date:  2009-03       Impact factor: 5.799

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  3 in total

Review 1.  MR elastography in primary sclerosing cholangitis: a pictorial review.

Authors:  Christopher L Welle; Patrick J Navin; Michael C Olson; Safa Hoodeshenas; Michael S Torbenson; Sudhakar K Venkatesh
Journal:  Abdom Radiol (NY)       Date:  2022-05-14

2.  Long-term Prognosis and Recurrence of Primary Sclerosing Cholangitis After Liver Transplantation: A Single-Center Experience.

Authors:  Yoshihide Ueda; Toshimi Kaido; Hideaki Okajima; Koichiro Hata; Takayuki Anazawa; Atsushi Yoshizawa; Shintaro Yagi; Kojiro Taura; Toshihiko Masui; Noriyo Yamashiki; Hironori Haga; Miki Nagao; Hiroyuki Marusawa; Hiroshi Seno; Shinji Uemoto
Journal:  Transplant Direct       Date:  2017-11-20

3.  Identification and clinical significance of nodular regenerative hyperplasia in primary sclerosing cholangitis.

Authors:  Nazli Begum Ozturk; Maria Isabel Fiel; Thomas D Schiano
Journal:  JGH Open       Date:  2022-07-19
  3 in total

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