Literature DB >> 23681863

Legionella pneumonia cases over a five-year period: a descriptive, retrospective study of outcomes in a UK district hospital.

Tom Wingfield1, Sam Rowell, Alex Peel, Deeksha Puli, Achyut Guleri, Rashmi Sharma.   

Abstract

As the recent outbreaks in Edinburgh and Camarthen, UK, have shown, Legionella pneumonia (LP) remains a significant public health problem, which is not only confined to those who have travelled abroad. In both outbreaks and sporadic cases, diagnosis can go unrecognised. We reviewed the demographics, comorbidities, diagnosis, treatment and clinical outcome of LP cases over five years in a district general hospital in northwest England. Over half of LP cases were UK acquired and 'classic' clinical features were common. Clinical criteria for diagnosing LP were confirmed, but few sputum samples were sent to reference laboratories, limiting further essential epidemiological mapping of UK cases. Following current UK community-acquired pneumonia guidance would have missed nearly one quarter of LP cases in our series, potentially leading to further morbidity and mortality.

Entities:  

Keywords:  CURB-65; Legionella; atypical; descriptive; outcome; pneumonia

Mesh:

Substances:

Year:  2013        PMID: 23681863      PMCID: PMC4952631          DOI: 10.7861/clinmedicine.13-2-152

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  34 in total

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Journal:  Eur J Clin Microbiol Infect Dis       Date:  2002-10-03       Impact factor: 3.267

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  5 in total

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Authors:  Shantini D Gamage; Natasha Ross; Stephen M Kralovic; Loretta A Simbartl; Gary A Roselle; Ruth L Berkelman; Allison T Chamberlain
Journal:  PLoS One       Date:  2021-01-11       Impact factor: 3.240

Review 4.  Legionnaires' Disease: Update on Diagnosis and Treatment.

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5.  Problem of immunoglobulin M co-detection in serological response to bacterial and viral respiratory pathogens among children suspected of legionellosis.

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