Literature DB >> 23681134

Early vascular healing with biodegradable polymer coated sirolimus-eluting coronary stent implantation: assessed by optical coherence tomography results at 4-month follow-up.

A Abhyankar1, J Prajapati, S Reddy, S Reddy.   

Abstract

AIM: The aim of this study was to evaluate the strut apposition and neointimal coverage of Supralimus-Core stent struts at 4 months after implantation using optical coherence tomography (OCT).
METHODS: The Supralimus-Core OCT study is a retrospective, single-center study evaluating strut apposition and neointimal coverage with OCT at 4 months after stent implantation. A total of 12 patients, who had 15 stents implanted were included in the study. The OCT was obtained using a C7-XR FD-OCT (frequency-domain OCT) intravascular imaging system. Strut apposition, neointimal hyperplasia (NIH) thickness and stent coverage on each stent strut were evaluated.
RESULTS: A total of 2870 struts and 1950 frames were analyzed from 15 stents. Average stent length was 29.3 mm. Average reference vessel diameter was 2.64 mm. Among 12 patients, 3 (25.0%) patients were with diabetes, 4 (26.7%) type B2 and 10 (66.7%) type C lesions. The apposed and covered struts were 2787 (97.11%), whereas malapposed and covered struts were 3 (0.10%), apposed and uncovered 49 (1.71%) and malapposed and uncovered 31 (1.08%). Mean NIH thickness was 155.1±55.2 µm.
CONCLUSION: The present study suggests that Supralimus-Core stent has a favorable vascular healing pattern at 4 months after stent implantation in terms of stent-strut coverage and strut apposition. This information indicates that the Supralimus-Core stent is a promising solution for decreasing late stent restenosis and preventing stent thrombosis.

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Year:  2013        PMID: 23681134

Source DB:  PubMed          Journal:  Minerva Cardioangiol        ISSN: 0026-4725            Impact factor:   1.347


  5 in total

1.  Evaluation of clinical outcomes in patients undergoing dual vessel percutaneous coronary intervention using sirolimus-eluting coronary stent system in India.

Authors:  Prakash Chandwani; Jayesh Prajapati; Sanjay Porwal; Bhavesh Khambhati; Ashok Thakkar
Journal:  J Clin Diagn Res       Date:  2015-02-01

2.  Learning from the Cardiologists and Developing Eluting Stents Targeting the Mtor Pathway for Pulmonary Application; A Future Concept for Tracheal Stenosis.

Authors:  Paul Zarogoulidis; Kaid Darwiche; Kosmas Tsakiridis; Helmut Teschler; Lonny Yarmus; Konstantinos Zarogoulidis; Lutz Freitag
Journal:  J Mol Genet Med       Date:  2013-08-26

3.  Preliminary Evaluation of Clinical and Angiographic Outcomes with Biodegradable Polymer Coated Sirolimus-Eluting Stent in De Novo Coronary Artery Disease: Results of the MANIPAL-FLEX Study.

Authors:  Ranjan Shetty; Jayesh Prajapati; Umesh Pai; Kiran Shetty
Journal:  Scientifica (Cairo)       Date:  2016-08-14

Review 4.  Drug Eluting Stents for Malignant Airway Obstruction: A Critical Review of the Literature.

Authors:  Wolfgang Hohenforst-Schmidt; Paul Zarogoulidis; Georgia Pitsiou; Bernd Linsmeier; Drosos Tsavlis; Ioannis Kioumis; Eleni Papadaki; Lutz Freitag; Theodora Tsiouda; J Francis Turner; Robert Browning; Michael Simoff; Nikolaos Sachpekidis; Kosmas Tsakiridis; Bojan Zaric; Lonny Yarmus; Sofia Baka; Grigoris Stratakos; Harald Rittger
Journal:  J Cancer       Date:  2016-01-13       Impact factor: 4.207

5.  Prospective evaluation of an ultrathin strut biodegradable polymer-coated sirolimus-eluting stent: 12 months' results from the S-FLEX UK registry.

Authors:  Anirban Choudhury; Scot Garg; Jamie Smith; Andrew Sharp; Sergio Nabais de Araujo; Anoop Chauhan; Nikhil Patel; Benjamin Wrigley; Sudipta Chattopadhyay; Azfar G Zaman
Journal:  BMJ Open       Date:  2019-10-11       Impact factor: 2.692

  5 in total

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