BACKGROUND: Unusual delusional syndromes are rare protean diseases with speculative etiopathogenic mechanisms. METHODS: Seven consecutive patients with advanced PD were evaluated over a 15-year period at the Movement Disorders Unit in the Neurology Service, Hospital de Clínicas, Federal University of Paraná, and the Paraná State Parkinson's Patients Association. RESULTS: We describe advanced Parkinson's disease patients presenting with unusual delusional syndromes, including cases of Ekbom, Othello, Capgras' and Diogenes syndromes, reduplicative paramnesia and mirrored-self misidentification. CONCLUSION: There are a few isolated reports of unusual neuropsychiatric disorders in patients with PD. We believe that these syndromes associated with advanced PD in elderly patients presenting with cognitive impairment and polypharmacy are probably often underestimated. Neurologists should be aware for these rare and treatable conditions.
BACKGROUND: Unusual delusional syndromes are rare protean diseases with speculative etiopathogenic mechanisms. METHODS: Seven consecutive patients with advanced PD were evaluated over a 15-year period at the Movement Disorders Unit in the Neurology Service, Hospital de Clínicas, Federal University of Paraná, and the Paraná State Parkinson'sPatients Association. RESULTS: We describe advanced Parkinson's diseasepatients presenting with unusual delusional syndromes, including cases of Ekbom, Othello, Capgras' and Diogenes syndromes, reduplicative paramnesia and mirrored-self misidentification. CONCLUSION: There are a few isolated reports of unusual neuropsychiatric disorders in patients with PD. We believe that these syndromes associated with advanced PD in elderly patients presenting with cognitive impairment and polypharmacy are probably often underestimated. Neurologists should be aware for these rare and treatable conditions.
Authors: Antonino Cannas; Mario Meloni; Marcello Mario Mascia; Paolo Solla; Luigi Cocco; Antonella Muroni; Gianluca Floris; Francesca Di Stefano; Francesco Marrosu Journal: Neurol Sci Date: 2016-11-15 Impact factor: 3.307
Authors: Patrick M J H Kemperman; Tristan V M Bruijn; Nienke C C Vulink; Mieke M C Mulder Journal: Acta Derm Venereol Date: 2022-03-08 Impact factor: 3.875
Authors: Dominic H Ffytche; Joana B Pereira; Clive Ballard; K Ray Chaudhuri; Daniel Weintraub; Dag Aarsland Journal: J Neurol Neurosurg Psychiatry Date: 2017-04 Impact factor: 10.154