PURPOSE: This systematic review focuses on the relationship between nocturia and depression/anxiety. Our objective is to provide an overview of current data on the epidemiology, pathophysiology and patient management implications of the association between nocturia and depression/anxiety. MATERIALS AND METHODS: We queried PubMed®, Web of Science® and Embase™ in July 2012 to identify abstracts, and original, review and editorial articles on nocturia and mood disorders, specifically depression and anxiety. The search was done using the key words "nocturia," "depression" and "anxiety." We complied with the Assessment of Multiple Systemic Reviews (AMSTAR) instrument. We retrieved a total of 500 records, including 95, 81 and 324 from PubMed, Web of Science and Embase, respectively. RESULTS: Cross-sectional (level 3) data indicated that nocturia and depression/anxiety are strongly associated. One prospective study contended that depression leads to nocturia in a unidirectional relationship. Nocturia poses a greater risk for depression in men vs women. Results conflict on the effect of serotonin reuptake inhibitors on nocturia. CONCLUSIONS: The results of this systematic review suggest a bidirectional association between depression and nocturia. The relationship between anxiety and nocturia is less clear. Practicing clinicians should consider administering a brief self-administered scale to assess for depression in patients with nocturia.
PURPOSE: This systematic review focuses on the relationship between nocturia and depression/anxiety. Our objective is to provide an overview of current data on the epidemiology, pathophysiology and patient management implications of the association between nocturia and depression/anxiety. MATERIALS AND METHODS: We queried PubMed®, Web of Science® and Embase™ in July 2012 to identify abstracts, and original, review and editorial articles on nocturia and mood disorders, specifically depression and anxiety. The search was done using the key words "nocturia," "depression" and "anxiety." We complied with the Assessment of Multiple Systemic Reviews (AMSTAR) instrument. We retrieved a total of 500 records, including 95, 81 and 324 from PubMed, Web of Science and Embase, respectively. RESULTS: Cross-sectional (level 3) data indicated that nocturia and depression/anxiety are strongly associated. One prospective study contended that depression leads to nocturia in a unidirectional relationship. Nocturia poses a greater risk for depression in men vs women. Results conflict on the effect of serotonin reuptake inhibitors on nocturia. CONCLUSIONS: The results of this systematic review suggest a bidirectional association between depression and nocturia. The relationship between anxiety and nocturia is less clear. Practicing clinicians should consider administering a brief self-administered scale to assess for depression in patients with nocturia.
Authors: Beverley J Shea; Candyce Hamel; George A Wells; Lex M Bouter; Elizabeth Kristjansson; Jeremy Grimshaw; David A Henry; Maarten Boers Journal: J Clin Epidemiol Date: 2009-02-20 Impact factor: 6.437
Authors: Varant Kupelian; John T Wei; Michael P O'Leary; Jens Peter Norgaard; Raymond C Rosen; John B McKinlay Journal: Eur Urol Date: 2011-09-10 Impact factor: 20.096
Authors: Timothy V Johnson; Ammara Abbasi; Samantha S Ehrlich; Renee S Kleris; Charles L Raison; Viraj A Master Journal: Urology Date: 2011-01 Impact factor: 2.649
Authors: Alayne D Markland; Camille P Vaughan; Theodore M Johnson; Patricia S Goode; David T Redden; Kathryn L Burgio Journal: J Urol Date: 2011-01-19 Impact factor: 7.450
Authors: Jukka T Häkkinen; Rahman Shiri; Juha Koskimäki; Teuvo L J Tammela; Anssi Auvinen; Matti Hakama Journal: J Urol Date: 2008-03-18 Impact factor: 7.450
Authors: Varant Kupelian; Raymond C Rosen; Carol L Link; Kevin T McVary; Lalitha Padmanabhan Aiyer; Patrick Mollon; Steven A Kaplan; John B McKinlay Journal: J Urol Date: 2008-12-16 Impact factor: 7.450
Authors: Karin S Coyne; Alan J Wein; Andrea Tubaro; Chris C Sexton; Christine L Thompson; Zoe S Kopp; Lalitha P Aiyer Journal: BJU Int Date: 2009-04 Impact factor: 5.588
Authors: Kari A O Tikkinen; Anssi Auvinen; Theodore M Johnson; Jeffrey P Weiss; Tapani Keränen; Aila Tiitinen; Olli Polo; Markku Partinen; Teuvo L J Tammela Journal: Am J Epidemiol Date: 2009-06-10 Impact factor: 4.897
Authors: Thomas F Monaghan; Donald L Bliwise; Nicholas R Suss; Matthew R Epstein; Zhan D Wu; Kyle P Michelson; Christina W Agudelo; Dennis J Robins; Adrian Wagg; Jeffrey P Weiss Journal: J Clin Sleep Med Date: 2019-04-15 Impact factor: 4.062
Authors: Benjamin N Breyer; Wen-Yi Huang; Charles S Rabkin; John F Alderete; Ratna Pakpahan; Tracey S Beason; Stacey A Kenfield; Jerome Mabie; Lawrence Ragard; Kathleen Y Wolin; Robert L Grubb; Gerald L Andriole; Siobhan Sutcliffe Journal: BJU Int Date: 2015-04-23 Impact factor: 5.588