A case report on autosomal recessive total congenital anonychia.

A 21-year-old woman presented with a history of the absence of the nails of all her fingers and toes since birth. Her grandfathers were first degree relatives. Her two brothers (26 and 28 years old) had the same anomalies. Autosomal recessive inheritance of this disease was supported in our cases because the parents were consanguineous and the disease occurred in two brothers and a sister.