Literature DB >> 23679050

Vulvar and vaginal atrophy in postmenopausal women: findings from the REVIVE (REal Women's VIews of Treatment Options for Menopausal Vaginal ChangEs) survey.

Sheryl A Kingsberg1, Susan Wysocki, Leslie Magnus, Michael L Krychman.   

Abstract

INTRODUCTION: Vulvar and vaginal atrophy (VVA) is a chronic medical condition experienced by many postmenopausal women. Symptoms include dyspareunia (pain with intercourse), vaginal dryness, and irritation and may affect sexual activities, relationships, and activities of daily life. AIM: The aim of this study is to characterize postmenopausal women's experience with and perception of VVA symptoms, interactions with healthcare professionals (HCPs), and available treatment options.
METHODS: An online survey was conducted in the United States in women from KnowledgePanel(®) , a 56,000-member probability-selected Internet panel projectable to the overall US population. Altogether, 3,046 postmenopausal women with VVA symptoms (the largest US cohort of recent surveys) responded to questions about their knowledge of VVA, impact of symptoms on their activities, communication with HCPs, and use of available treatments. MAIN OUTCOME MEASURES: Percent is calculated as the ratio of response over total responding for each question for all and stratified participants.
RESULTS: The most common VVA symptoms were dryness (55% of participants), dyspareunia (44%), and irritation (37%). VVA symptoms affected enjoyment of sex in 59% of participants. Additionally, interference with sleep, general enjoyment of life, and temperament were reported by 24%, 23%, and 23% of participants, respectively. Few women attributed symptoms to menopause (24%) or hormonal changes (12%). Of all participants, 56% had ever discussed VVA symptoms with an HCP and 40% currently used VVA-specific topical treatments (vaginal over-the-counter [OTC] products [29%] and vaginal prescription therapies [11%]). Of those who had discussed symptoms with an HCP, 62% used OTC products. Insufficient symptom relief and inconvenience were cited as major limitations of OTC products and concerns about side effects and cancer risk limited use of topical vaginal prescription therapies.
CONCLUSIONS: VVA symptoms are common in postmenopausal women. Significant barriers to treatment include lack of knowledge about VVA, reluctance to discuss symptoms with HCPs, safety concerns, inconvenience, and inadequate symptom relief from available treatments.
© 2013 International Society for Sexual Medicine.

Entities:  

Keywords:  Dyspareunia; Postmenopausal Women; Sexual Relationships; Survey; Vaginal Dryness; Vulvar and Vaginal Atrophy

Mesh:

Year:  2013        PMID: 23679050     DOI: 10.1111/jsm.12190

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  69 in total

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Review 3.  Menopause and Sexuality.

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Journal:  Endocrinol Metab Clin North Am       Date:  2015-09       Impact factor: 4.741

4.  Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial.

Authors:  Susan J Diem; Katherine A Guthrie; Caroline M Mitchell; Susan D Reed; Joseph C Larson; Kristine E Ensrud; Andrea Z LaCroix
Journal:  Menopause       Date:  2018-10       Impact factor: 2.953

Review 5.  Female Sexual Function at Midlife and Beyond.

Authors:  Holly N Thomas; Genevieve S Neal-Perry; Rachel Hess
Journal:  Obstet Gynecol Clin North Am       Date:  2018-10-25       Impact factor: 2.844

6.  Management of Potential Long-Term Toxicities in Breast Cancer Patients.

Authors:  C C O'Sullivan; K J Ruddy
Journal:  Curr Breast Cancer Rep       Date:  2016-10-13

7.  Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem.

Authors:  Caroline M Mitchell; Sujatha Srinivasan; Anna Plantinga; Michael C Wu; Susan D Reed; Katherine A Guthrie; Andrea Z LaCroix; Tina Fiedler; Matthew Munch; Congzhou Liu; Noah G Hoffman; Ian A Blair; Katherine Newton; Ellen W Freeman; Hadine Joffe; Lee Cohen; David N Fredricks
Journal:  Menopause       Date:  2018-05       Impact factor: 2.953

8.  Prevalence and correlates of vaginal estrogenization in postmenopausal women in the United States.

Authors:  Stacy Tessler Lindau; Annie Dude; Natalia Gavrilova; Joscelyn N Hoffmann; L Philip Schumm; Martha K McClintock
Journal:  Menopause       Date:  2017-05       Impact factor: 2.953

9.  Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial.

Authors:  Caroline M Mitchell; Susan D Reed; Susan Diem; Joseph C Larson; Katherine M Newton; Kristine E Ensrud; Andrea Z LaCroix; Bette Caan; Katherine A Guthrie
Journal:  JAMA Intern Med       Date:  2018-05-01       Impact factor: 21.873

10.  Effect of vaginal estrogen on pessary use.

Authors:  Sybil G Dessie; Katherine Armstrong; Anna M Modest; Michele R Hacker; Lekha S Hota
Journal:  Int Urogynecol J       Date:  2016-03-18       Impact factor: 2.894

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