Literature DB >> 23678429

Antiviral activity of natural products extracted from marine organisms.

Bushra Uzair1, Zahra Mahmood, Sobia Tabassum.   

Abstract

Many epidemics have broken out over the centuries. Hundreds and thousands of humans have died over a disease. Available treatments for infectious diseases have always been limited. Some infections are more deadly than the others, especially viral pathogens. These pathogens have continuously resisted all kinds of medical treatment, due to a need for new treatments to be developed. Drugs are present in nature and are also synthesized in vitro and they help in combating diseases and restoring health. Synthesizing drugs is a hard and time consuming task, which requires a lot of man power and financial aid. However, the natural compounds are just lying around on the earth, may it be land or water. Over a thousand novel compounds isolated from marine organisms are used as antiviral agents. Others are being pharmacologically tested. Today, over forty antiviral compounds are present in the pharmacological market. Some of these compounds are undergoing clinical and preclinical stages. Marine compounds are paving the way for a new trend in modern medicine.

Entities:  

Keywords:  Antiviral Compounds; HIV; Marine Life-Forms; Pharmacology

Year:  2011        PMID: 23678429      PMCID: PMC3648973          DOI: 10.5681/bi.2011.029

Source DB:  PubMed          Journal:  Bioimpacts        ISSN: 2228-5652


  34 in total

1.  Microspinosamide, a new HIV-inhibitory cyclic depsipeptide from the marine sponge Sidonops microspinosa.

Authors:  M A Rashid; K R Gustafson; L K Cartner; N Shigematsu; L K Pannell; M R Boyd
Journal:  J Nat Prod       Date:  2001-01       Impact factor: 4.050

2.  The potential molecular targets of marine sulfated polymannuroguluronate interfering with HIV-1 entry. Interaction between SPMG and HIV-1 rgp120 and CD4 molecule.

Authors:  Geng Meiyu; Li Fuchuan; Xin Xianliang; Li Jing; Yan Zuowei; Guan Huashi
Journal:  Antiviral Res       Date:  2003-07       Impact factor: 5.970

3.  In vitro inhibition of the replication of haemorrhagic septicaemia virus (VHSV) and African swine fever virus (ASFV) by extracts from marine microalgae.

Authors:  J Fabregas; D García; M Fernandez-Alonso; A I Rocha; P Gómez-Puertas; J M Escribano; A Otero; J M Coll
Journal:  Antiviral Res       Date:  1999-11       Impact factor: 5.970

4.  Galactans from cystocarpic plants of the red seaweed Callophyllis variegata (Kallymeniaceae, Gigartinales).

Authors:  María C Rodríguez; Emilia R Merino; Carlos A Pujol; Elsa B Damonte; Alberto S Cerezo; María C Matulewicz
Journal:  Carbohydr Res       Date:  2005-11-09       Impact factor: 2.104

5.  Mechanism of inhibition of a poxvirus topoisomerase by the marine natural product sansalvamide A.

Authors:  Y Hwang; D Rowley; D Rhodes; J Gertsch; W Fenical; F Bushman
Journal:  Mol Pharmacol       Date:  1999-06       Impact factor: 4.436

6.  Structural analysis and antiviral activity of a sulfated galactan from the red seaweed Schizymenia binderi (Gigartinales, Rhodophyta).

Authors:  Betty Matsuhiro; Ana F Conte; Elsa B Damonte; Adriana A Kolender; María C Matulewicz; Enrique G Mejías; Carlos A Pujol; Elisa A Zúñiga
Journal:  Carbohydr Res       Date:  2005-10-31       Impact factor: 2.104

7.  Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava.

Authors:  Murat Artan; Yong Li; Fatih Karadeniz; Sang-Hoon Lee; Moon-Moo Kim; Se-Kwon Kim
Journal:  Bioorg Med Chem       Date:  2008-07-29       Impact factor: 3.641

8.  Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei.

Authors:  Pinaki Mandal; Carlos A Pujol; María J Carlucci; Kausik Chattopadhyay; Elsa B Damonte; Bimalendu Ray
Journal:  Phytochemistry       Date:  2008-06-21       Impact factor: 4.072

9.  The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme.

Authors:  Claudio Cesar Cirne-Santos; Thiago Moreno L Souza; Valéria L Teixeira; Carlos Frederico L Fontes; Moacyr A Rebello; Luiz Roberto R Castello-Branco; Celina M Abreu; Amílcar Tanuri; Izabel C P P Frugulhetti; Dumith Chequer Bou-Habib
Journal:  Antiviral Res       Date:  2007-09-06       Impact factor: 5.970

10.  Thalassiolins A-C: new marine-derived inhibitors of HIV cDNA integrase.

Authors:  David C Rowley; Mark S T Hansen; Denise Rhodes; Christoph A Sotriffer; Haihong Ni; J Andrew McCammon; Frederic D Bushman; William Fenical
Journal:  Bioorg Med Chem       Date:  2002-11       Impact factor: 3.641

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  3 in total

1.  Anti HSV-1 activity of halistanol sulfate and halistanol sulfate C isolated from Brazilian marine sponge Petromica citrina (Demospongiae).

Authors:  Tatiana da Rosa Guimarães; Carlos Guillermo Quiroz; Caroline Rigotto Borges; Simone Quintana de Oliveira; Maria Tereza Rojo de Almeida; Éverson Miguel Bianco; Maria Izabel Goulart Moritz; João Luís Carraro; Jorge Alejandro Palermo; Gabriela Cabrera; Eloir Paulo Schenkel; Flávio Henrique Reginatto; Cláudia Maria Oliveira Simões
Journal:  Mar Drugs       Date:  2013-10-29       Impact factor: 5.118

2.  Computational Simulations Identified Marine-Derived Natural Bioactive Compounds as Replication Inhibitors of SARS-CoV-2.

Authors:  Vikas Kumar; Shraddha Parate; Sanghwa Yoon; Gihwan Lee; Keun Woo Lee
Journal:  Front Microbiol       Date:  2021-04-21       Impact factor: 5.640

3.  Natural Products as Potential Antiviral Drugs: The Specific Case of Marine Biotoxins.

Authors: 
Journal:  Russ J Bioorg Chem       Date:  2021-12-16       Impact factor: 0.796

  3 in total

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