Literature DB >> 23678177

Analysis of the role of vaccinia virus H7 in virion membrane biogenesis with an H7-deletion mutant.

Xiangzhi Meng1, Xiang Wu, Bo Yan, Junpeng Deng, Yan Xiang.   

Abstract

Essential vaccinia virus genes are often studied with conditional-lethal inducible mutants. Here, we constructed a deletion mutant lacking the essential H7R gene (the ΔH7 mutant) with an H7-expressing cell line. Compared to an inducible H7 mutant, the ΔH7 mutant showed a defect at an earlier step of virion membrane biogenesis, before the development of short crescent-shaped precursors of the viral envelope. Our studies refine the role of H7 in virion membrane biogenesis and highlight the values of analyzing deletion mutants.

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Year:  2013        PMID： 23678177      PMCID： PMC3700178          DOI： 10.1128/JVI.00845-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Characterization of early stages in vaccinia virus membrane biogenesis: implications of the 21-kilodalton protein and a newly identified 15-kilodalton envelope protein.

Authors:  J R Rodríguez; C Risco; J L Carrascosa; M Esteban; D Rodríguez
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

2.  Construction of a vaccinia virus deficient in the essential DNA repair enzyme uracil DNA glycosylase by a complementing cell line.

Authors:  G W Holzer; F G Falkner
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

3.  Analysis of viral membranes formed in cells infected by a vaccinia virus L2-deletion mutant suggests their origin from the endoplasmic reticulum.

Authors:  Liliana Maruri-Avidal; Andrea S Weisberg; Himani Bisht; Bernard Moss
Journal:  J Virol       Date:  2012-11-28       Impact factor: 5.103

4.  Vaccinia virus A17L open reading frame encodes an essential component of nascent viral membranes that is required to initiate morphogenesis.

Authors:  E J Wolffe; D M Moore; P J Peters; B Moss
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

5.  Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells.

Authors:  G A Ward; C K Stover; B Moss; T R Fuerst
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

6.  Vaccinia virus 15-kilodalton (A14L) protein is essential for assembly and attachment of viral crescents to virosomes.

Authors:  J R Rodríguez; C Risco; J L Carrascosa; M Esteban; D Rodríguez
Journal:  J Virol       Date:  1998-02       Impact factor: 5.103

7.  Elucidating the essential role of the A14 phosphoprotein in vaccinia virus morphogenesis: construction and characterization of a tetracycline-inducible recombinant.

Authors:  P Traktman; K Liu; J DeMasi; R Rollins; S Jesty; B Unger
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

8.  Vaccinia virus nonstructural protein encoded by the A11R gene is required for formation of the virion membrane.

Authors:  Wolfgang Resch; Andrea S Weisberg; Bernard Moss
Journal:  J Virol       Date:  2005-06       Impact factor: 5.103

9.  Temperature-sensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis.

Authors:  P Traktman; A Caligiuri; S A Jesty; K Liu; U Sankar
Journal:  J Virol       Date:  1995-10       Impact factor: 5.103

10.  Deep-etch EM reveals that the early poxvirus envelope is a single membrane bilayer stabilized by a geodetic "honeycomb" surface coat.

Authors:  John Heuser
Journal:  J Cell Biol       Date:  2005-04-25       Impact factor: 10.539
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  8 in total

Review 1.  Poxvirus membrane biogenesis.

Authors:  Bernard Moss
Journal:  Virology       Date:  2015-02-26       Impact factor: 3.616

2.  Direct formation of vaccinia virus membranes from the endoplasmic reticulum in the absence of the newly characterized L2-interacting protein A30.5.

Authors:  Liliana Maruri-Avidal; Andrea S Weisberg; Bernard Moss
Journal:  J Virol       Date:  2013-09-11       Impact factor: 5.103

3.  Vaccinia Virus A6 Is a Two-Domain Protein Requiring a Cognate N-Terminal Domain for Full Viral Membrane Assembly Activity.

Authors:  Xiangzhi Meng; Lloyd Rose; Yue Han; Junpeng Deng; Yan Xiang
Journal:  J Virol       Date:  2017-04-28       Impact factor: 5.103

4.  Enigmatic origin of the poxvirus membrane from the endoplasmic reticulum shown by 3D imaging of vaccinia virus assembly mutants.

Authors:  Andrea S Weisberg; Liliana Maruri-Avidal; Himani Bisht; Bryan T Hansen; Cindi L Schwartz; Elizabeth R Fischer; Xiangzhi Meng; Yan Xiang; Bernard Moss
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-04       Impact factor: 11.205

5.  Deletion of the Vaccinia Virus I2 Protein Interrupts Virion Morphogenesis, Leading to Retention of the Scaffold Protein and Mislocalization of Membrane-Associated Entry Proteins.

Authors:  Seong-In Hyun; Andrea Weisberg; Bernard Moss
Journal:  J Virol       Date:  2017-07-12       Impact factor: 5.103

6.  Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.

Authors:  Swapna Kolli; Xiangzhi Meng; Xiang Wu; Djoshkun Shengjuler; Craig E Cameron; Yan Xiang; Junpeng Deng
Journal:  J Virol       Date:  2014-12-03       Impact factor: 5.103

7.  Structure-Function Analysis of Two Interacting Vaccinia Proteins That Are Critical for Viral Morphogenesis: L2 and A30.5.

Authors:  Juliana Debrito Carten; Matthew Greseth; Paula Traktman
Journal:  J Virol       Date:  2021-11-03       Impact factor: 6.549

Review 8.  From crescent to mature virion: vaccinia virus assembly and maturation.

Authors:  Liang Liu; Tamara Cooper; Paul M Howley; John D Hayball
Journal:  Viruses       Date:  2014-10-07       Impact factor: 5.048
  8 in total

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