Beth A Tarini1, William H Herman, Joyce M Lee. 1. Child Health Evaluation and Research, University of Michigan, Ann Arbor, MI 48109-5456, USA. btarini@umich.edu
Abstract
OBJECTIVE: To examine the effect of hypothetical genetic susceptibility test results on diabetic parents' intention to prevent type 2 diabetes (T2D) in their children. METHODS: Parents with T2D indicated their intention to prevent T2D in their youngest child at baseline and after a hypothetical positive and negative T2D genetic test result. We calculated mean/median "preventive intention scores" for each scenario and examined the association between parents' score change and parent/child characteristics. RESULTS: A total of 63% of parents reported that their child had "almost no risk" or "slight risk" of developing T2D. Parents' median baseline preventive intention score was 8. It increased to 10 after a positive test result and decreased to 5 after a negative test result. CONCLUSIONS: Negative T2D genetic susceptibility test results may decrease diabetic parents' intentions to prevent T2D for their children. Future research studies in a real-life clinical context should examine this phenomenon.
OBJECTIVE: To examine the effect of hypothetical genetic susceptibility test results on diabetic parents' intention to prevent type 2 diabetes (T2D) in their children. METHODS: Parents with T2D indicated their intention to prevent T2D in their youngest child at baseline and after a hypothetical positive and negative T2D genetic test result. We calculated mean/median "preventive intention scores" for each scenario and examined the association between parents' score change and parent/child characteristics. RESULTS: A total of 63% of parents reported that their child had "almost no risk" or "slight risk" of developing T2D. Parents' median baseline preventive intention score was 8. It increased to 10 after a positive test result and decreased to 5 after a negative test result. CONCLUSIONS: Negative T2D genetic susceptibility test results may decrease diabetic parents' intentions to prevent T2D for their children. Future research studies in a real-life clinical context should examine this phenomenon.
Entities:
Keywords:
children; diabetes mellitus; genetic testing; type 2 diabetes; vignettes
Authors: Michael M Engelgau; Linda S Geiss; Jinan B Saaddine; James P Boyle; Stephanie M Benjamin; Edward W Gregg; Edward F Tierney; Nilka Rios-Burrows; Ali H Mokdad; Earl S Ford; Giuseppina Imperatore; K M Venkat Narayan Journal: Ann Intern Med Date: 2004-06-01 Impact factor: 25.391
Authors: Robert J Kuczmarski; Cynthia L Ogden; Shumei S Guo; Laurence M Grummer-Strawn; Katherine M Flegal; Zuguo Mei; Rong Wei; Lester R Curtin; Alex F Roche; Clifford L Johnson Journal: Vital Health Stat 11 Date: 2002-05
Authors: William C Knowler; Elizabeth Barrett-Connor; Sarah E Fowler; Richard F Hamman; John M Lachin; Elizabeth A Walker; David M Nathan Journal: N Engl J Med Date: 2002-02-07 Impact factor: 91.245