Literature DB >> 23675569

A rare der(Y)t(Y;1)(q12;q12) in a patient with post-polycythemic myelofibrosis: a case report.

Masahiro Manabe1, Osami Takeda, Junya Okita, Teruhito Takakuwa, Naonori Harada, Hirofumi Nakano, Shuichiro Okamoto, Yasutaka Aoyama, Takeo Kumura, Tadanobu Ohta, Yoshio Furukawa, Atsuko Mugitani.   

Abstract

We describe a case of post-polycythemic myelofibrosis harboring der(Y)t(Y;1)(q12;q12). The patient was a 69-year-old man and was initially diagnosed with polycythemia vera. During the clinical course of his condition, the polycythemia developed into myelofibrosis. Chromosome analysis detected der(Y)t(Y;1)(q12;q12). We discuss the association between der(Y)t(Y;1)(q11~12;q12~21) and tumorigenesis along with a review of literature.

Entities:  

Keywords:  Post-polycythemic myelofibrosis; chromosomal abnormality; der(Y)t(Y;1)(q12;q12)

Year:  2013        PMID： 23675569      PMCID： PMC3649809     

Source DB:  PubMed          Journal:  Am J Blood Res        ISSN： 2160-1992


  23 in total

Review 1.  Spectral karyotyping refined the identification of a der(Y)t(Y;1)(q11.1 or.2;q12) in the blast cells of a patient with atypical chronic myeloid leukemia.

Authors:  Akimichi Ohsaka; Tomoko Hisa
Journal:  Acta Haematol       Date:  2002       Impact factor: 2.195

Review 2.  Karyotype and molecular cytogenetic studies in polycythemia vera.

Authors:  Joris Loup Andrieux; Jean Loup Demory
Journal:  Curr Hematol Rep       Date:  2005-05

3.  JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis.

Authors:  Paola Guglielmelli; Giovanni Barosi; Lisa Pieri; Elisabetta Antonioli; Alberto Bosi; Alessandro M Vannucchi
Journal:  Haematologica       Date:  2008-11-27       Impact factor: 9.941

4.  Prognosis of patients with t(8;16)(p11;p13) acute myeloid leukemia.

Authors:  Tanya Brown; John Swansbury; Mary M Taj
Journal:  Leuk Lymphoma       Date:  2011-09-23

5.  der(Y)t(Y;1) is a nonrandom abnormality in myelodysplastic syndrome.

Authors:  D C Wei; T S Wan; L C Chan; P N Cheng
Journal:  Cancer Genet Cytogenet       Date:  1993-10-15

6.  Derivative (1;18)(q10;q10): a recurrent and novel unbalanced translocation involving 1q in myeloid disorders.

Authors:  T S Wan; S K Ma; W Y Au; L C Chan
Journal:  Cancer Genet Cytogenet       Date:  2001-07-01

Review 7.  Chromosome 1 abnormalities in myeloid malignancies: a literature survey and karyotype-phenotype associations.

Authors:  Domenica Caramazza; Kebede Hussein; Sergio Siragusa; Animesh Pardanani; Ryan A Knudson; Rhett P Ketterling; Ayalew Tefferi
Journal:  Eur J Haematol       Date:  2009-11-30       Impact factor: 2.997

8.  Pattern of trisomy 1q in hematological malignancies: a single institution experience.

Authors:  Vesna Djordjević; Marija Dencić-Fekete; Jelica Jovanović; Danijela Drakulić; Milena Stevanović; Gradimir Janković; Mirjana Gotić
Journal:  Cancer Genet Cytogenet       Date:  2008-10

9.  Chromosome abnormalities may correlate with prognosis in Burkitt/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08.

Authors:  Mark A Lones; Warren G Sanger; Michelle M Le Beau; Nyla A Heerema; Richard Sposto; Sherrie L Perkins; Jonathan Buckley; Marshall E Kadin; Carl R Kjeldsberg; Anna Meadows; Stuart Siegel; Jonathan Finlay; Sharon Bergeron; Mitchell S Cairo
Journal:  J Pediatr Hematol Oncol       Date:  2004-03       Impact factor: 1.289

10.  Karyotypic patterns and their clinical significance in polycythemia vera.

Authors:  J R Testa; J R Kanofsky; J D Rowley; J M Baron; J W Vardiman
Journal:  Am J Hematol       Date:  1981       Impact factor: 10.047
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