BACKGROUND: High trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis. METHODS: In a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months. RESULTS: At 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL. CONCLUSIONS: The course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.
BACKGROUND: High trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis. METHODS: In a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months. RESULTS: At 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL. CONCLUSIONS: The course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.
Authors: Mirjam P J Bogaarts; Brenda L Den Oudsten; Jan A Roukema; Johanna M G H Van Riel; Laurens V Beerepoot; Jolanda De Vries Journal: Support Care Cancer Date: 2011-08-24 Impact factor: 3.603
Authors: Helen J Michielsen; Alida F W Van der Steeg; Jan A Roukema; Jolanda De Vries Journal: Support Care Cancer Date: 2007-02-07 Impact factor: 3.603
Authors: Mirjam P J Bogaarts; Brenda L Den Oudsten; Jan A Roukema; Johanna M G H Van Riel; Laurens V Beerepoot; Jolanda De Vries Journal: Support Care Cancer Date: 2010-09-04 Impact factor: 3.603
Authors: Germina-Alina Cosma; Alina Chiracu; Amalia Raluca Stepan; Marian Alexandru Cosma; Marian Costin Nanu; Florin Voinea; Khalid Walid Bibi; Cătălin Păunescu; Monoem Haddad Journal: Int J Environ Res Public Health Date: 2021-04-12 Impact factor: 3.390