Literature DB >> 23674127

Five new sesquiterpene lactones from Inula hupehensis.

Jie Ren1, Jiang Jiang Qin, Xiang Rong Cheng, Shi Kai Yan, Hui Zi Jin, Wei Dong Zhang.   

Abstract

Four new pseudoguaianolides (1-4), one new guaianolide (5), together with ten known compounds (6-15) were isolated from the aerial parts of Inula hupehensis. Their structures were elucidated mainly on the basis of 1D and 2D spectroscopic methods and circular dichroism analysis. In addition, compounds 1-10 and 13 were tested for their inhibitory effects against LPS-induced NO production in RAW264.7 macrophages. Compounds 2, 6, 8 and 9 exhibited significant inhibitory activities with IC50 values in the range of 0.6-6.6 μM.

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Year:  2013        PMID： 23674127     DOI： 10.1007/s12272-013-0135-1

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  4 in total

1.  Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives.

Authors:  Yulin Ren; Gerardo D Anaya-Eugenio; Austin A Czarnecki; Tran Ngoc Ninh; Chunhua Yuan; Hee-Byung Chai; Djaja D Soejarto; Joanna E Burdette; Esperanza J Carcache de Blanco; A Douglas Kinghorn
Journal:  Bioorg Med Chem       Date:  2018-07-17       Impact factor: 3.641

2.  Chemical Constituents from the Flowers of Carthamus tinctorius L. and Their Lung Protective Activity.

Authors:  Yanling Liu; Mengna Wang; Yangang Cao; Mengnan Zeng; Qinqin Zhang; Yingjie Ren; Xu Chen; Chen He; Xiling Fan; Xiaoke Zheng; Weisheng Feng
Journal:  Molecules       Date:  2022-06-02       Impact factor: 4.927

3.  Anti-Hepatocellular Carcinoma (HepG2) Activities of Monoterpene Hydroxy Lactones Isolated from the Marine Microalga Tisochrysis Lutea.

Authors:  Katkam N Gangadhar; Maria João Rodrigues; Hugo Pereira; Helena Gaspar; F Xavier Malcata; Luísa Barreira; João Varela
Journal:  Mar Drugs       Date:  2020-11-19       Impact factor: 5.118

4.  Constituents of Xerolekia speciosissima (L.) Anderb. (Inuleae), and Anti-Inflammatory Activity of 7,10-Diisobutyryloxy-8,9-epoxythymyl Isobutyrate.

Authors:  Natalia Kłeczek; Janusz Malarz; Barbara Gierlikowska; Anna K Kiss; Anna Stojakowska
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411
  4 in total

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