PURPOSE: The purpose of this study is to compare the surgical and imaging outcome in children who underwent brain tumour surgery with intention of complete tumour resection, prior to and following the start of intra-operative MRI (ioMRI) service. METHODS: ioMRI service for brain tumour resection commenced in October 2009. A cohort of patients operated between June 2007 and September 2009 with a pre-surgical intention of complete tumour resection were selected (Group A). A similar number of consecutive cases were selected from a prospective database of patients undergoing ioMRI (Group B). The demographics, imaging, pathology and surgical outcome of both groups were compared. RESULTS: Thirty-six of 47 cases from Group A met the inclusion criterion and 36 cases were selected from Group B; 7 of the 36 cases in Group A had unequivocal evidence of residual tumour on the post-operative scan; 5 (14%) of them underwent repeat resection within 6 months post-surgery. In Group B, ioMRI revealed unequivocal evidence of residual tumour in 11 of the 36 cases following initial resection. In 10 of these 11 cases, repeat resections were performed during the same surgical episode and none of these 11 cases required repeat surgery in the following 6 months. Early repeat resection rate was significantly different between both groups (p = 0.003). CONCLUSION: Following the advent of ioMRI at our institution, the need for repeat resection within 6 months has been prevented in cases where ioMRI revealed unequivocal evidence of residual tumour.
PURPOSE: The purpose of this study is to compare the surgical and imaging outcome in children who underwent brain tumour surgery with intention of complete tumour resection, prior to and following the start of intra-operative MRI (ioMRI) service. METHODS: ioMRI service for brain tumour resection commenced in October 2009. A cohort of patients operated between June 2007 and September 2009 with a pre-surgical intention of complete tumour resection were selected (Group A). A similar number of consecutive cases were selected from a prospective database of patients undergoing ioMRI (Group B). The demographics, imaging, pathology and surgical outcome of both groups were compared. RESULTS: Thirty-six of 47 cases from Group A met the inclusion criterion and 36 cases were selected from Group B; 7 of the 36 cases in Group A had unequivocal evidence of residual tumour on the post-operative scan; 5 (14%) of them underwent repeat resection within 6 months post-surgery. In Group B, ioMRI revealed unequivocal evidence of residual tumour in 11 of the 36 cases following initial resection. In 10 of these 11 cases, repeat resections were performed during the same surgical episode and none of these 11 cases required repeat surgery in the following 6 months. Early repeat resection rate was significantly different between both groups (p = 0.003). CONCLUSION: Following the advent of ioMRI at our institution, the need for repeat resection within 6 months has been prevented in cases where ioMRI revealed unequivocal evidence of residual tumour.
Authors: Manish N Shah; Jeffrey R Leonard; Gabrielle Inder; Feng Gao; Michael Geske; Devon H Haydon; Melvin E Omodon; John Evans; Diego Morales; Ralph G Dacey; Matthew D Smyth; Michael R Chicoine; David D Limbrick Journal: J Neurosurg Pediatr Date: 2012-03 Impact factor: 2.375
Authors: Ron Levy; Robin G Cox; Walter J Hader; Terry Myles; Garnette R Sutherland; Mark G Hamilton Journal: J Neurosurg Pediatr Date: 2009-11 Impact factor: 2.375
Authors: J H Wisoff; J M Boyett; M S Berger; C Brant; H Li; A J Yates; P McGuire-Cullen; P A Turski; L N Sutton; J C Allen; R J Packer; J L Finlay Journal: J Neurosurg Date: 1998-07 Impact factor: 5.115
Authors: Bassel Zebian; Francesco Vergani; José Pedro Lavrador; Soumya Mukherjee; William John Kitchen; Vita Stagno; Christos Chamilos; Benedetta Pettorini; Conor Mallucci Journal: CNS Oncol Date: 2016-12-21
Authors: Christopher Paul Millward; Sandra Perez Da Rosa; Shivaram Avula; Jonathan R Ellenbogen; Michaela Spiteri; Emma Lewis; Mo Didi; Conor Mallucci Journal: Childs Nerv Syst Date: 2015-07-28 Impact factor: 1.475