Literature DB >> 23673321

MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.

Suyoun Chung, Yusuke Nakamura.   

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Year:  2013        PMID： 23673321     DOI： 10.4161/cc.24988

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  21 in total

Review 1.  Exploiting replicative stress to treat cancer.

Authors:  Matthias Dobbelstein; Claus Storgaard Sørensen
Journal:  Nat Rev Drug Discov       Date:  2015-05-08       Impact factor: 84.694

2.  Computational insights into the binding of IN17 inhibitors to MELK.

Authors:  Matthew Harger; Ju-Hyeon Lee; Brandon Walker; Juliana M Taliaferro; Ramakrishna Edupuganti; Kevin N Dalby; Pengyu Ren
Journal:  J Mol Model       Date:  2019-05-08       Impact factor: 1.810

3.  Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.

Authors:  Houda Alachkar; Martin B G Mutonga; Klaus H Metzeler; Noreen Fulton; Gregory Malnassy; Tobias Herold; Karsten Spiekermann; Stefan K Bohlander; Wolfgang Hiddemann; Yo Matsuo; Wendy Stock; Yusuke Nakamura
Journal:  Oncotarget       Date:  2014-12-15

4.  MELK-a conserved kinase: functions, signaling, cancer, and controversy.

Authors:  Ranjit Ganguly; Ahmed Mohyeldin; Jordyn Thiel; Harley I Kornblum; Monique Beullens; Ichiro Nakano
Journal:  Clin Transl Med       Date:  2015-03-07

5.  OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases.

Authors:  Wenbin Ji; Christopher Arnst; Aaron R Tipton; Michael E Bekier; William R Taylor; Tim J Yen; Song-Tao Liu
Journal:  PLoS One       Date:  2016-04-15       Impact factor: 3.240

6.  Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development.

Authors:  Luay Aswad; Surya Pavan Yenamandra; Ghim Siong Ow; Oleg Grinchuk; Anna V Ivshina; Vladimir A Kuznetsov
Journal:  Oncotarget       Date:  2015-11-03

7.  Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.

Authors:  Suyoun Chung; Kyoko Kijima; Aiko Kudo; Yoshiko Fujisawa; Yosuke Harada; Akiko Taira; Naofumi Takamatsu; Takashi Miyamoto; Yo Matsuo; Yusuke Nakamura
Journal:  Oncotarget       Date:  2016-04-05

8.  Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway.

Authors:  Tao Du; Ying Qu; Jianfang Li; Hao Li; Liping Su; Quan Zhou; Min Yan; Chen Li; Zhenggang Zhu; Bingya Liu
Journal:  Mol Cancer       Date:  2014-05-04       Impact factor: 27.401

9.  Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma.

Authors:  Suely Kazue Nagahashi Marie; Sueli Mieko Oba-Shinjo; Roseli da Silva; Marcela Gimenez; Gisele Nunes Reis; Jean-Pierre Tassan; Jose Cesar Rosa; Miyuki Uno
Journal:  Proteome Sci       Date:  2016-03-11       Impact factor: 2.480

10.  Comprehensive Bioinformatics Analysis of mRNA Expression Profiles and Identification of a miRNA-mRNA Network Associated with the Pathogenesis of Low-Grade Gliomas.

Authors:  Ming Wang; Yan Cui; Yang Cai; Yugang Jiang; Yong Peng
Journal:  Cancer Manag Res       Date:  2021-06-29       Impact factor: 3.989
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