Literature DB >> 23672830

Keratocystic odontogenic tumor: a retrospective analysis of genetic, immunohistochemical and therapeutic features. Proposal of a multicenter clinical survey tool.

Michael W Finkelstein1, John W Hellstein, Kimberly S Lake, Steven D Vincent.   

Abstract

OBJECTIVE: In 2005, the World Health Organization reclassified the parakeratinizing odontogenic keratocyst as a neoplasm. This article reviews the research leading to this reclassification, and validates a new survey tool that can be easily used to pool surgical and recurrence data from multiple offices. STUDY
DESIGN: All odontogenic lesions accessioned in the Iowa Surgical Oral Pathology Laboratory between 1949 and 2010 were identified from the database. A survey tool to assess treatment and follow-up was created. A total of 46 surgeons agreed to participate.
RESULTS: A total of 70 keratocystic odontogenic tumors (KOTs) had documented recurrences at follow-up intervals ranging from 6 months to 5 years. Primary tumors that recurred ranged in size as measured by greatest radiographic diameter from 0.7 to 6 cm.
CONCLUSIONS: This survey tool is recommended as standard allowing treatment of cases by multiple practitioners to be compared retrospectively or prospectively.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23672830     DOI: 10.1016/j.oooo.2013.03.018

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol


  6 in total

1.  Recurrence of nonsyndromic odontogenic keratocyst after marsupialization and delayed enucleation vs. enucleation alone: a systematic review and meta-analysis.

Authors:  Yuri Slusarenko da Silva; Paul J W Stoelinga; Maria da Graça Naclério-Homem
Journal:  Oral Maxillofac Surg       Date:  2018-11-29

2.  Molecular Signaling in Benign Odontogenic Neoplasia Pathogenesis.

Authors:  Hope M Amm; Mary MacDougall
Journal:  Curr Oral Health Rep       Date:  2016-03-31

3.  Five years follow-up of a keratocyst odontogenic tumor treated by marsupialization and enucleation: A case report and literature review.

Authors:  Rafael Scaf de Molon; Mario H Verzola; Luana C Pires; Vinicius I Mascarenhas; Rodrigo B da Silva; Joni A Cirelli; Roberto H Barbeiro
Journal:  Contemp Clin Dent       Date:  2015-03

4.  Role of Carnoy's solution in the treatment of keratocystic odontogenic tumor: A systematic review.

Authors:  Á Díaz-Belenguer; A Sánchez-Torres; C Gay-Escoda
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-11-01

5.  Keratocystic odontogenic tumor: A biopsy service's experience with 104 solitary, multiple and recurrent lesions.

Authors:  I-O Bello
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-09-01

6.  Investigation of clinicopathological parameters and expression of COX-2, bcl-2, PCNA, and p53 in primary and recurrent sporadic odontogenic keratocysts.

Authors:  Tomasz Kaczmarzyk; Konrad Kisielowski; Rafał Koszowski; Magdalena Rynkiewicz; Ewa Gawełek; Karolina Babiuch; Anna Bednarczyk; Bogna Drozdzowska
Journal:  Clin Oral Investig       Date:  2018-03-05       Impact factor: 3.573

  6 in total

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