| Literature DB >> 23670946 |
Kazuhiro Morisaki1, Masanao Sawa, Jun-ya Nomaguchi, Hiroyuki Morimoto, Yosuke Takeuchi, Kazushi Mashima, Takashi Ohshima.
Abstract
A green way to amino acids: α-Tetrasubstituted α-amino acid derivatives are formed in high yield and enantioselectivity by using a Rh-catalyzed enantioselective alkynylation of α-ketiminoesters. This reaction, which involves a proton transfer and can be conducted at room temperature, has high substrate scope (see scheme; Cbz = benzyloxycarbonyl, Fmoc = 9-fluorenylmethyloxycarbonyl).Entities:
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Year: 2013 PMID： 23670946 DOI： 10.1002/chem.201301237
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236