Literature DB >> 23670133

Viscoelastic flow-focusing in microchannels: scaling properties of the particle radial distributions.

Giovanni Romeo1, Gaetano D'Avino, Francesco Greco, Paolo A Netti, Pier Luca Maffettone.   

Abstract

Particles suspended in non-Newtonian liquids flowing in channels may migrate transversally to the main flow direction as a result of normal stress gradients. Viscoelasticity-induced migration has proven to be an efficient mechanism to promote 3D flow-focusing in cylindrical microchannels, avoiding the need for complex and expensive apparati. In this work, we demonstrate the existence of a single dimensionless number (Θ) that governs the migration dynamics of particles in viscoelastic liquids flowing in micropipes at low Deborah numbers (Deborah number is the ratio of fluid and flow characteristic times). The definition of Θ in terms of the relevant fluid, flow and geometrical quantities is obtained by generalizing the particle migration velocity expression given in previous asymptotic analytical theories through numerical simulations. An extensive experimental investigation quantitatively confirms the novel predictions: the experimental particle distributions along the channel axial direction collapse on a single curve when rescaled in terms of the proposed dimensionless number. The results reported in this work give a simple and general way to define the flow-focusing conditions promoted by viscoelastic effects.

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Year:  2013        PMID: 23670133     DOI: 10.1039/c3lc50257k

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  9 in total

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2.  Biophysical investigation of living monocytes in flow by collaborative coherent imaging techniques.

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3.  In-flow real-time detection of spectrally encoded microgels for miRNA absolute quantification.

Authors:  David Dannhauser; Filippo Causa; Edmondo Battista; Angela M Cusano; Domenico Rossi; Paolo A Netti
Journal:  Biomicrofluidics       Date:  2016-12-06       Impact factor: 2.800

4.  Elasto-inertial microfluidics for bacteria separation from whole blood for sepsis diagnostics.

Authors:  Muhammad Asim Faridi; Harisha Ramachandraiah; Indradumna Banerjee; Sahar Ardabili; Sergey Zelenin; Aman Russom
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5.  Focusing and alignment of erythrocytes in a viscoelastic medium.

Authors:  Taesik Go; Hyeokjun Byeon; Sang Joon Lee
Journal:  Sci Rep       Date:  2017-01-24       Impact factor: 4.379

Review 6.  A Review of Microfluidic Devices for Rheological Characterisation.

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Journal:  Micromachines (Basel)       Date:  2022-01-22       Impact factor: 2.891

7.  A weakly supervised deep learning approach for label-free imaging flow-cytometry-based blood diagnostics.

Authors:  Corin F Otesteanu; Martina Ugrinic; Gregor Holzner; Yun-Tsan Chang; Christina Fassnacht; Emmanuella Guenova; Stavros Stavrakis; Andrew deMello; Manfred Claassen
Journal:  Cell Rep Methods       Date:  2021-10-25

8.  Multiplex particle focusing via hydrodynamic force in viscoelastic fluids.

Authors:  Doo Jin Lee; Howard Brenner; Jae Ryoun Youn; Young Seok Song
Journal:  Sci Rep       Date:  2013-11-19       Impact factor: 4.379

9.  Single-cell screening of multiple biophysical properties in leukemia diagnosis from peripheral blood by pure light scattering.

Authors:  David Dannhauser; Domenico Rossi; Mimmo Ripaldi; Paolo A Netti; Filippo Causa
Journal:  Sci Rep       Date:  2017-10-04       Impact factor: 4.379

  9 in total

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