Literature DB >> 23668420

Asymmetric synthesis of tetrahydro-β-carbolines via chiral phosphoric acid catalyzed transfer hydrogenation reaction.

Qin Yin1, Shou-Guo Wang, Shu-Li You.   

Abstract

Chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of hydroxylactams has been realized to provide enantioenriched tetrahydro-β-carbolines in dioxane at room temperature (up to 94% yield, 90% ee).

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Year:  2013        PMID： 23668420     DOI： 10.1021/ol400995c

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Chiral Brønsted Acid-Catalyzed Enantioselective α-Amidoalkylation Reactions: A Joint Experimental and Predictive Study.

Authors:  Eider Aranzamendi; Sonia Arrasate; Nuria Sotomayor; Humberto González-Díaz; Esther Lete
Journal:  ChemistryOpen       Date:  2016-11-23       Impact factor: 2.911

2.  Internal acidity scale and reactivity evaluation of chiral phosphoric acids with different 3,3'-substituents in Brønsted acid catalysis.

Authors:  Kerstin Rothermel; Maxime Melikian; Johnny Hioe; Julian Greindl; Johannes Gramüller; Matej Žabka; Nils Sorgenfrei; Thomas Hausler; Fabio Morana; Ruth M Gschwind
Journal:  Chem Sci       Date:  2019-09-06       Impact factor: 9.825

3.  Bifunctional thiosquaramide catalyzed asymmetric reduction of dihydro-β-carbolines and enantioselective synthesis of (-)-coerulescine and (-)-horsfiline by oxidative rearrangement.

Authors:  Manda Sathish; Fabiane M Nachtigall; Leonardo S Santos
Journal:  RSC Adv       Date:  2020-10-21       Impact factor: 4.036
  3 in total

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