Literature DB >> 23667067

Prothrombin complex concentrate for warfarin-induced bleeding in a patient with a mechanical aortic valve.

Rahul Kar1, Erik Abel, Pamela Burcham, Michael S Firstenberg.   

Abstract

Reversal of anticoagulation-induced bleeding in the perioperative period can be challenging, particularly with an unstable patient with a mechanical valve. We present a case of life-threatening bleeding successfully managed with a prothrombin complex concentrate as an alternative to fresh frozen plasma.

Entities:  

Keywords:  Bleeding; Blood; Coagulation/anticoagulation

Mesh：

Substances：

Year:  2013        PMID： 23667067      PMCID： PMC3715198          DOI： 10.1093/icvts/ivt207

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN： 1569-9285


  5 in total

Review 1.  Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Anne Holbrook; Sam Schulman; Daniel M Witt; Per Olav Vandvik; Jason Fish; Michael J Kovacs; Peter J Svensson; David L Veenstra; Mark Crowther; Gordon H Guyatt
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

Review 2.  Clinical review: Prothrombin complex concentrates--evaluation of safety and thrombogenicity.

Authors:  Benny Sørensen; Donat R Spahn; Petra Innerhofer; Michael Spannagl; Rolf Rossaint
Journal:  Crit Care       Date:  2011-01-12       Impact factor: 9.097

3.  Thromboembolic safety and efficacy of prothrombin complex concentrates in the emergency reversal of warfarin coagulopathy.

Authors:  Ammar Majeed; Anna Eelde; Anna Agren; Sam Schulman; Margareta Holmström
Journal:  Thromb Res       Date:  2011-07-31       Impact factor: 3.944

4.  Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial.

Authors:  I Pabinger; B Brenner; U Kalina; S Knaub; A Nagy; H Ostermann
Journal:  J Thromb Haemost       Date:  2008-01-15       Impact factor: 5.824

5.  A promising new alternative for the rapid reversal of warfarin coagulopathy in traumatic intracranial hemorrhage.

Authors:  Marian N Safaoui; Roshanak Aazami; Heidi Hotz; Matthew T Wilson; Daniel R Margulies
Journal:  Am J Surg       Date:  2008-08-22       Impact factor: 2.565
  5 in total
  2 in total

Review 1.  Prothrombin Complex Concentrates for Perioperative Vitamin K Antagonist and Non-vitamin K Anticoagulant Reversal.

Authors:  Jerrold H Levy; James Douketis; Thorsten Steiner; Joshua N Goldstein; Truman J Milling
Journal:  Anesthesiology       Date:  2018-12       Impact factor: 7.892

2.  Four factor prothrombin complex concentrate for warfarin reversal in patients with left ventricular assist devices.

Authors:  Jessica Rimsans; Amy Levesque; Erin Lyons; Katelyn Sylvester; Michael M Givertz; Mandeep R Mehra; Garrick C Stewart; Jean M Connors
Journal:  J Thromb Thrombolysis       Date:  2018-08       Impact factor: 2.300
  2 in total

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