Literature DB >> 23666512

Nerve-oriented mesorectal excision (NOME): autonomic nerves as landmarks for laparoscopic rectal resection.

Norbert Runkel1, Harald Reiser.   

Abstract

PURPOSE: We have developed nerve-oriented mesorectal excision (NOME) as a novel concept in rectal cancer surgery by which autonomic pelvic nerves serve as landmarks for a standardized navigation along fascial planes. This article describes the technique step by step and presents our results from 2008 to 2012.
MATERIAL AND METHODS: The key steps are: preparation of the splanchnic nerves at the mid-posterior sidewall, the hypogastric nerves at the upper sidewall, and the urogenital nerve branches (Walsh) at the caudal-anterior sidewall. The dissection of the lateral ligament is strictly performed as the last step. NOME was applied in 274 consecutive mesorectal excisions (partial 20.4%, total 79.6%); a subgroup of 42 male patients underwent a questionnaire-based interview on sexual activity.
RESULTS: The conversion rate was 0.7%. High (complete) specimen quality and circumferential margin negativity were achieved in 90.1% and 95.3%, respectively. Anastomotic leaks occurred in 13 (4.7%) patients. Mortality was 1.8%. The frequency of prolonged urinary catheter was 1.8%. Of 22 sexually active males interviewed, 18 (81.8%) maintained activity postoperatively.
CONCLUSIONS: NOME achieves high-quality mesorectal specimens and a high rate of preservation of autonomic nerve function. The concept of using nerves as laparoscopic landmarks may help to standardize and master laparoscopic rectal cancer surgery.

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Year:  2013        PMID: 23666512     DOI: 10.1007/s00384-013-1705-x

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  40 in total

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2.  Urogenital function following laparoscopic and open rectal cancer resection: a comparative study.

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Journal:  Surg Endosc       Date:  2012-04-05       Impact factor: 4.584

3.  Laparoscopic resection in rectal cancer patients: outcome and cost-benefit analysis.

Authors:  Marco Braga; Matteo Frasson; Andrea Vignali; Walter Zuliani; Giovanni Capretti; Valerio Di Carlo
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4.  Voiding and sexual dysfunction after deep rectal resection and total mesorectal excision: prospective study on 52 patients.

Authors:  Peter Sterk; Bijan Shekarriz; Svetlana Günter; Jan Nolde; Robert Keller; Hans-Peter Bruch; Hodjat Shekarriz
Journal:  Int J Colorectal Dis       Date:  2005-04-22       Impact factor: 2.571

5.  Laparoscopic pelvic autonomic nerve-preserving surgery for patients with lower rectal cancer after chemoradiation therapy.

Authors:  Jin-Tung Liang; Hong-Shiee Lai; Po-Huang Lee
Journal:  Ann Surg Oncol       Date:  2007-04       Impact factor: 5.344

6.  Male sexual and urinary function after laparoscopic total mesorectal excision.

Authors:  Mario Morino; Umberto Parini; Marco Ettore Allaix; Gabriella Monasterolo; Riccardo Brachet Contul; Corrado Garrone
Journal:  Surg Endosc       Date:  2008-10-15       Impact factor: 4.584

7.  Total mesorectal excision in the operative treatment of carcinoma of the rectum.

Authors:  W E Enker; H T Thaler; M L Cranor; T Polyak
Journal:  J Am Coll Surg       Date:  1995-10       Impact factor: 6.113

8.  Randomized clinical trial comparing laparoscopic and open surgery in patients with rectal cancer.

Authors:  J Lujan; G Valero; Q Hernandez; A Sanchez; M D Frutos; P Parrilla
Journal:  Br J Surg       Date:  2009-09       Impact factor: 6.939

9.  Laparoscopic-assisted versus open abdominoperineal resection for low rectal cancer: a prospective randomized trial.

Authors:  Simon S M Ng; Ka Lau Leung; Janet F Y Lee; Raymond Y C Yiu; Jimmy C M Li; Anthony Y B Teoh; Wing Wa Leung
Journal:  Ann Surg Oncol       Date:  2008-04-05       Impact factor: 5.344

10.  The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

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1.  [Intraoperative pitfalls and complications in defecation disorders and rectal prolapse].

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2.  [Hybrid TAMIS total mesorectal excision. A new perspective in treatment of distal rectal cancer - Technique and results].

Authors:  A D Rink; D W Kauff; M Paschold; K-H Vestweber; H Lang; W Kneist
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3.  The urogenital-hypogastric sheath: an anatomical observation on the relationship between the inferomedial extension of renal fascia and the hypogastric nerves.

Authors:  X F Yang; G H Luo; Z H Ding; G X Li; X W Chen; S Z Zhong
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4.  Reappraisal of the lateral rectal ligament: an anatomical study of total mesorectal excision with autonomic nerve preservation.

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Journal:  Int J Colorectal Dis       Date:  2018-03-19       Impact factor: 2.571

Review 5.  Sexual dysfunction following rectal cancer surgery.

Authors:  V Celentano; R Cohen; J Warusavitarne; O Faiz; M Chand
Journal:  Int J Colorectal Dis       Date:  2017-05-11       Impact factor: 2.571

6.  To what extent is the low anterior resection syndrome (LARS) associated with quality of life as measured using the EORTC C30 and CR38 quality of life questionnaires?

Authors:  Juliane Kupsch; Matthias Kuhn; Klaus E Matzel; Joerg Zimmer; Olga Radulova-Mauersberger; Anja Sims; Helmut Witzigmann; Sigmar Stelzner
Journal:  Int J Colorectal Dis       Date:  2019-02-05       Impact factor: 2.571

7.  Outcome of bowel function following anterior resection for rectal cancer-an analysis using the low anterior resection syndrome (LARS) score.

Authors:  Juliane Kupsch; Thomas Jackisch; Klaus E Matzel; Joerg Zimmer; Andreas Schreiber; Anja Sims; Helmut Witzigmann; Sigmar Stelzner
Journal:  Int J Colorectal Dis       Date:  2018-03-15       Impact factor: 2.571

Review 8.  Pelvic autonomic nerve preservation in radical rectal cancer surgery: changes in the past 3 decades.

Authors:  Min-Hoe Chew; Yu-Ting Yeh; Evan Lim; Francis Seow-Choen
Journal:  Gastroenterol Rep (Oxf)       Date:  2016-07-31

9.  Magnetic resonance neuroimaging promotes the preservation of pelvic autonomic nerves in laparoscopic total mesorectal excision: a comparative study.

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Journal:  Ann Transl Med       Date:  2021-12

10.  Surgeons' assessment of internal anal sphincter nerve supply during TaTME - inbetween expectations and reality.

Authors:  Werner Kneist; Laura Hanke; Daniel W Kauff; Hauke Lang
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