Advanced drug delivery in motion.

After 50 years of research on advanced drug delivery systems the time has come to critically reflect upon the past achievements. Despite some successes, many hurdles still need to be overcome before we can quantitatively deliver therapeutically relevant amounts of drug molecules to any desired location within the human body. In this commentary, I give my opinion on how to improve the current generation of nanocarriers for drug delivery. In addition, I speculate on which direction the drug delivery field should be going in order to fulfill the "magic bullet" dream in the long run.