| Literature DB >> 23663773 |
Colleen J Winstead1, Casey T Weaver.
Abstract
Defining determinants of T cell fate is central to understanding adaptive immunity and the design of effective vaccines. Tubo et al. demonstrate that intrinsic properties of T cell receptor signaling dictate whether CD4 T cells adopt predominantly type 1 helper or follicular helper T cell phenotypes in response to bacterial or viral infection.Entities:
Year: 2013 PMID： 23663773 DOI： 10.1016/j.cell.2013.04.026
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582