M N Tanko1, M A Kayembe, F Cainelli, S Vento. 1. Departments of Pathology and Internal Medicine, School of Medicine, Faculty of Health Sciences University of Botswana, Gaborone, Botswana. comexet@yahoo.co.uk
Abstract
BACKGROUND: To determine the frequency and pattern of malignant tumours of the female genital tract among Batswana women. DESIGN: A four-year retrospective histological study of the pattern of female genital tract malignancy in Botswana. SETTING: University of Botswana and the National Health Laboratory Gaborone, Botswana. The National Health Laboratory is the only public tertiary referral laboratory that provides diagnostic pathology services in the South-Eastern part of Botswana. It is located just adjacent to Princess Marina Hospital, the major tertiary referral hospital in the country. METHODS: All histologically confirmed diagnoses of female genital tract malignancies from January 1(st) 2006 to December 31(st) 2009 were reviewed by two pathologists and diagnoses re-confirmed by taking fresh tissue sections from paraffin embedded archival tissue blocks. RESULTS: The age of patients ranged from 13-96 years with a mean age of 54.5 ± 6.4 years. Cancer of the cervix constituted 80.6%, followed by uterine cancer (10.0%), carcinomas of the vulva (4.5%) and ovary (3.4%) in that order. Ovarian cancers predominated in the younger age group. There was a steady increase in the frequencies of cervical, uterine and ovarian cancers over the 4-year study period with a decline in uterine cancer in the 4(th) year. CONCLUSION: Cervical cancer incidence is high among Batswana women and all female genital tract cancers occurred at a relatively early mean age. Therefore the importance of established and accessible screening programs and awareness campaigns need more emphasis than it is being given currently.
BACKGROUND: To determine the frequency and pattern of malignant tumours of the female genital tract among Batswana women. DESIGN: A four-year retrospective histological study of the pattern of female genital tract malignancy in Botswana. SETTING: University of Botswana and the National Health Laboratory Gaborone, Botswana. The National Health Laboratory is the only public tertiary referral laboratory that provides diagnostic pathology services in the South-Eastern part of Botswana. It is located just adjacent to Princess Marina Hospital, the major tertiary referral hospital in the country. METHODS: All histologically confirmed diagnoses of female genital tract malignancies from January 1(st) 2006 to December 31(st) 2009 were reviewed by two pathologists and diagnoses re-confirmed by taking fresh tissue sections from paraffin embedded archival tissue blocks. RESULTS: The age of patients ranged from 13-96 years with a mean age of 54.5 ± 6.4 years. Cancer of the cervix constituted 80.6%, followed by uterine cancer (10.0%), carcinomas of the vulva (4.5%) and ovary (3.4%) in that order. Ovarian cancers predominated in the younger age group. There was a steady increase in the frequencies of cervical, uterine and ovarian cancers over the 4-year study period with a decline in uterine cancer in the 4(th) year. CONCLUSION: Cervical cancer incidence is high among Batswana women and all female genital tract cancers occurred at a relatively early mean age. Therefore the importance of established and accessible screening programs and awareness campaigns need more emphasis than it is being given currently.
Authors: Kenneth O Simbiri; Hem C Jha; Mukendi K Kayembe; Carrie Kovarik; Erle S Robertson Journal: Infect Agent Cancer Date: 2014-08-24 Impact factor: 2.965