AIMS AND OBJECTIVES: To determine the common aetiolog of acute bacterial meningitis in children and their antibiotic susceptibility pattern. MATERIALS AND METHODS: A retrospective study with a review of cerebrospinal fluid culture reports of paediatric patients aged 0-15 years, suspected of acute meningitis in the Medical Microbiology Department of Aminu Kano Teaching Hospital, Kano, Nigeria from October 2006 to October 2009 from October 2006 to October 2009. RESULTS: A positive culture bacterial isolation rate of 3.3% (n=50/1500) with prevalence of Streptococcus pneumoniae (24%), Neisseria meningitidis (22%), Escherichia coli (16%), Haemophilus influenzae (14%), Group B streptococci (8%) and Enterococci (8%) which were susceptible to ceftriaxone (96%), cefotaxime (95%) and ciprofloxacin (93%) across the bacterial isolates. Neonates were 55% (n=6.8/12.4) most at risk. CONCLUSION: Neonates are the most at risk of acute bacterial meningitis. In the absence of antibiotic susceptibility report, ceftriaxone should be considered as a first choice reliable antibiotic for empirical treatment of meningitis in children, in this environment.
AIMS AND OBJECTIVES: To determine the common aetiolog of acute bacterial meningitis in children and their antibiotic susceptibility pattern. MATERIALS AND METHODS: A retrospective study with a review of cerebrospinal fluid culture reports of paediatric patients aged 0-15 years, suspected of acute meningitis in the Medical Microbiology Department of Aminu Kano Teaching Hospital, Kano, Nigeria from October 2006 to October 2009 from October 2006 to October 2009. RESULTS: A positive culture bacterial isolation rate of 3.3% (n=50/1500) with prevalence of Streptococcus pneumoniae (24%), Neisseria meningitidis (22%), Escherichia coli (16%), Haemophilus influenzae (14%), Group B streptococci (8%) and Enterococci (8%) which were susceptible to ceftriaxone (96%), cefotaxime (95%) and ciprofloxacin (93%) across the bacterial isolates. Neonates were 55% (n=6.8/12.4) most at risk. CONCLUSION: Neonates are the most at risk of acute bacterial meningitis. In the absence of antibiotic susceptibility report, ceftriaxone should be considered as a first choice reliable antibiotic for empirical treatment of meningitis in children, in this environment.
Authors: Pui-Ying Iroh Tam; Beth K Thielen; Stephen K Obaro; Ann M Brearley; Alexander M Kaizer; Haitao Chu; Edward N Janoff Journal: Vaccine Date: 2017-03-09 Impact factor: 3.641
Authors: Brenda A Kwambana-Adams; Jie Liu; Catherine Okoi; Jason M Mwenda; Nuredin I Mohammed; Enyonam Tsolenyanu; Lorna Awo Renner; Daniel Ansong; Beckie N Tagbo; Muhammad F Bashir; Mamadou Kourna Hama; Mouhamadou A Sonko; Jean Gratz; Archibald Worwui; Peter Ndow; Adam L Cohen; Fatima Serhan; Richard Mihigo; Martin Antonio; Eric Houpt Journal: Am J Trop Med Hyg Date: 2020-05-21 Impact factor: 2.345
Authors: Mohammed S Abdallah; Rune Philemon; Anaam Kadri; Ashley Al-Hinai; Aliasgher M Saajan; Joshua G Gidabayda; Gibson S Kibiki; Blandina T Mmbaga Journal: East Afr Health Res J Date: 2018-04-01