Literature DB >> 23659598

Two new neuroprotective phenolic compounds from Gastrodia elata.

Zhen-Chang Zhang1, Gang Su, Jiong Li, Hua Wu, Xiao-Dong Xie.   

Abstract

Two new phenolic compounds 4-(4'-hydroxybenzyl) phenyl glucoside (gastrodin B, 1) and 1'-hydroxymethyl-phenyl 4-hydroxy-3-(4″-hydroxybenzyl) benzyl ether (gastrol B, 2) were isolated from the rhizomes of Gastrodia elata. Their structures were elucidated on the basis of spectroscopic data and chemical reaction. All compounds exhibited potent neuroprotective activity against H2O2-induced PC12 cell damage.

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Year:  2013        PMID： 23659598     DOI： 10.1080/10286020.2013.791286

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  7 in total

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4.  Natural occurrence of bisphenol F in mustard.

Authors:  Otmar Zoller; Beat J Brüschweiler; Roxane Magnin; Hans Reinhard; Peter Rhyn; Heinz Rupp; Silvia Zeltner; Richard Felleisen
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5.  Simultaneous Qualitative Assessment and Quantitative Analysis of Metabolites (Phenolics, Nucleosides and Amino Acids) from the Roots of Fresh Gastrodia elata Using UPLC-ESI-Triple Quadrupole Ion MS and ESI- Linear Ion Trap High-Resolution MS.

Authors:  Sha Chen; Jun Qiu Liu; Hui Xiao; Jun Zhang; An Liu
Journal:  PLoS One       Date:  2016-03-08       Impact factor: 3.240

6.  Gastrodin protects MC3T3-E1 osteoblasts from dexamethasone-induced cellular dysfunction and promotes bone formation via induction of the NRF2 signaling pathway.

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Journal:  Int J Mol Med       Date:  2018-01-23       Impact factor: 4.101

Review 7.  Bibenzyls and bisbybenzyls of bryophytic origin as promising source of novel therapeutics: pharmacology, synthesis and structure-activity.

Authors:  Samapika Nandy; Abhijit Dey
Journal:  Daru       Date:  2020-08-15       Impact factor: 3.117
  7 in total

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