| Literature DB >> 23659368 |
Alain J Simpson1, Hon Wai Lam.
Abstract
2-Acetylazaarenes undergo catalytic enantioselective Michael additions to nitroalkenes in the presence of a chiral Ni(II)-bis(oxazoline) complex. The process is tolerant of a range of azines or azoles in the pronucleophilic component, resulting in Michael products in moderate to high enantioselectivities.Entities:
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Year: 2013 PMID： 23659368 DOI： 10.1021/ol400578c
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005