Literature DB >> 23658297

Discovering what makes STAT signaling TYK in T-ALL.

Lorena Fontan1, Ari Melnick.   

Abstract

SUMMARY: RNA interference screening establishes TYK2 dependence in T-cell acute lymphoblastic leukemia (T-ALL), leading to identification of TYK2-activating mutations and increased IL-10 receptor signaling in T-ALL cell lines. Cancer Discov; 3(5); 494-6. ©2013 AACR.

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Year:  2013        PMID： 23658297     DOI： 10.1158/2159-8290.CD-13-0123

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  2 in total

1.  Structural modeling of JAK1 mutations in T-cell acute lymphoblastic leukemia reveals a second contact site between pseudokinase and kinase domains.

Authors:  Kirsten Canté-Barrett; Joost C M Uitdehaag; Jules P P Meijerink
Journal:  Haematologica       Date:  2016-01-27       Impact factor: 9.941

2.  STAT1 regulates MD-2 expression in monocytes of sepsis via miR-30a.

Authors:  Yanhong Wang; Tiehua Li; Benquan Wu; Hui Liu; Jinmei Luo; Dingyun Feng; Yunfeng Shi
Journal:  Inflammation       Date:  2014-12       Impact factor: 4.092
  2 in total

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