| Literature DB >> 23657262 |
Sang-Min Lee1, De-Hao Tsai, Vincent A Hackley, Martin W Brechbiel, Robert F Cook.
Abstract
We report a prototype approach to formulate gold nanoparticle-based X-ray absorbing agents through surface-engineering of a cisplatin pharmacophore with modified polyacrylate. The resulting agents exhibit both chemo-therapeutic potency to cancer cells and Auger-mediated secondary electron emission, showing great potential to improve the therapeutic efficacy of chemo-radiation.Entities:
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Year: 2013 PMID: 23657262 PMCID: PMC6957245 DOI: 10.1039/c3nr00333g
Source DB: PubMed Journal: Nanoscale ISSN: 2040-3364 Impact factor: 7.790