Literature DB >> 2365359

Repetitive sequence elements in an initiation locus of the amplified dihydrofolate reductase domain in CHO cells.

T H Leu1, B Anachkova, J L Hamlin.   

Abstract

We have previously demonstrated that one of the replication initiation loci in the dihydrofolate reductase (DHFR) domain of Chinese hamster cells contains a repeated sequence that is enriched in the early-replicating fraction of the Chinese hamster genome. Here we present the sequence of the initiation locus, identify the relevant repeated element, and show that, while this element is enriched in early-replicating DNA, its synthesis is not confined to early S.

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Year:  1990        PMID： 2365359     DOI： 10.1016/0888-7543(90)90178-w

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  10 in total

1.  Dynamics of association of origins of DNA replication with the nuclear matrix during the cell cycle.

Authors:  V Djeliova; G Russev; B Anachkova
Journal:  Nucleic Acids Res       Date:  2001-08-01       Impact factor: 16.971

2.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-05-25       Impact factor: 16.971

3.  Activation of a mammalian origin of replication by chromosomal rearrangement.

Authors:  T H Leu; J L Hamlin
Journal:  Mol Cell Biol       Date:  1992-06       Impact factor: 4.272

4.  Attachment to the nuclear matrix mediates specific alterations in chromatin structure.

Authors:  A Pemov; S Bavykin; J L Hamlin
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

5.  Isolation and cloning of putative mouse DNA replication initiation sites: binding to nuclear protein factors.

Authors:  D Dimitrova; L Vassilev; B Anachkova; G Russev
Journal:  Nucleic Acids Res       Date:  1993-12-11       Impact factor: 16.971

6.  Lagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase origin.

Authors:  S Wang; P A Dijkwel; J L Hamlin
Journal:  Mol Cell Biol       Date:  1998-01       Impact factor: 4.272

7.  The structure of adenovirus type 12 DNA integration sites in the hamster cell genome.

Authors:  M Knoblauch; J Schröer; B Schmitz; W Doerfler
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

8.  A winding road to origin discovery.

Authors:  Joyce L Hamlin; Larry D Mesner; Pieter A Dijkwel
Journal:  Chromosome Res       Date:  2010-01       Impact factor: 5.239

9.  Initiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine.

Authors:  P A Dijkwel; J L Hamlin
Journal:  Mol Cell Biol       Date:  1992-09       Impact factor: 4.272

10.  The dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.

Authors:  L D Mesner; X Li; P A Dijkwel; J L Hamlin
Journal:  Mol Cell Biol       Date:  2003-02       Impact factor: 4.272
  10 in total

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