Literature DB >> 23653463

HIF2 and endocrine neoplasia: an evolving story.

Eamonn R Maher1.   

Abstract

In this issue of Endocrine-Related Cancer, Toledo et al. report the identification of activating mutations in the HIF2 (EPAS1) transcription factor in a subset of sporadic pheochromocytomas and paragangliomas. These findings add significantly to an evolving and complex story of the role of hypoxic gene response pathways in human endocrine neoplasia.

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Year:  2013        PMID： 23653463     DOI： 10.1530/ERC-13-0146

Source DB:  PubMed          Journal:  Endocr Relat Cancer        ISSN： 1351-0088            Impact factor:   5.678


  5 in total

Review 1.  Pheochromocytoma and paraganglioma pathogenesis: learning from genetic heterogeneity.

Authors:  Patricia L M Dahia
Journal:  Nat Rev Cancer       Date:  2014-01-20       Impact factor: 60.716

Review 2.  What Have We Learned from Molecular Biology of Paragangliomas and Pheochromocytomas?

Authors:  Thomas G Papathomas; Diederik P D Suurd; Alfred K Lam; Ronald R de Krijger; Karel Pacak; Arthur S Tischler; Menno R Vriens
Journal:  Endocr Pathol       Date:  2021-01-12       Impact factor: 3.943

3.  The adrenal medulla and extra-adrenal paraganglia: then and now.

Authors:  Arthur S Tischler; Karel Pacak; Graeme Eisenhofer
Journal:  Endocr Pathol       Date:  2014-03       Impact factor: 3.943

4.  Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2α/androgen receptor signals.

Authors:  Jie Luo; Soo Ok Lee; Yun Cui; Rachel Yang; Lei Li; Chawnshang Chang
Journal:  Oncotarget       Date:  2015-09-29

5.  Identification of Novel Mutations and Expressions of EPAS1 in Phaeochromocytomas and Paragangliomas.

Authors:  Farhadul Islam; Suja Pillai; Vinod Gopalan; Alfred King-Yin Lam
Journal:  Genes (Basel)       Date:  2020-10-24       Impact factor: 4.096
  5 in total

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