Literature DB >> 23653178

LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis.

Wei Xu1, Yit-Heng Chooi, Jin W Choi, Shuang Li, John C Vederas, Nancy A Da Silva, Yi Tang.   

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Year:  2013        PMID： 23653178      PMCID： PMC3844545          DOI： 10.1002/anie.201302406

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  21 in total

1.  Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis.

Authors:  J Kennedy; K Auclair; S G Kendrew; C Park; J C Vederas; C R Hutchinson
Journal:  Science       Date:  1999-05-21       Impact factor: 47.728

2.  Biosynthesis of lovastatin analogs with a broadly specific acyltransferase.

Authors:  Xinkai Xie; Kenji Watanabe; Wladyslaw A Wojcicki; Clay C C Wang; Yi Tang
Journal:  Chem Biol       Date:  2006-11

3.  Efficient synthesis of simvastatin by use of whole-cell biocatalysis.

Authors:  Xinkai Xie; Yi Tang
Journal:  Appl Environ Microbiol       Date:  2007-02-02       Impact factor: 4.792

4.  Chaperone coexpression plasmids: differential and synergistic roles of DnaK-DnaJ-GrpE and GroEL-GroES in assisting folding of an allergen of Japanese cedar pollen, Cryj2, in Escherichia coli.

Authors:  K Nishihara; M Kanemori; M Kitagawa; H Yanagi; T Yura
Journal:  Appl Environ Microbiol       Date:  1998-05       Impact factor: 4.792

5.  Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene.

Authors:  L Hendrickson; C R Davis; C Roach; D K Nguyen; T Aldrich; P C McAda; C D Reeves
Journal:  Chem Biol       Date:  1999-07

6.  Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans.

Authors:  I Fujii; A Watanabe; U Sankawa; Y Ebizuka
Journal:  Chem Biol       Date:  2001-02

7.  A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading.

Authors:  Meng Wang; Hui Zhou; Monica Wirz; Yi Tang; Christopher N Boddy
Journal:  Biochemistry       Date:  2009-07-14       Impact factor: 3.162

8.  Acyltransferase mediated polyketide release from a fungal megasynthase.

Authors:  Xinkai Xie; Michael J Meehan; Wei Xu; Pieter C Dorrestein; Yi Tang
Journal:  J Am Chem Soc       Date:  2009-06-24       Impact factor: 15.419

9.  The crystal structure of a mammalian fatty acid synthase.

Authors:  Timm Maier; Marc Leibundgut; Nenad Ban
Journal:  Science       Date:  2008-09-05       Impact factor: 47.728

10.  Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Authors:  A W Alberts; J Chen; G Kuron; V Hunt; J Huff; C Hoffman; J Rothrock; M Lopez; H Joshua; E Harris; A Patchett; R Monaghan; S Currie; E Stapley; G Albers-Schonberg; O Hensens; J Hirshfield; K Hoogsteen; J Liesch; J Springer
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205
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  29 in total

1.  Engineering Saccharomyces cerevisiae for production of simvastatin.

Authors:  Carly M Bond; Yi Tang
Journal:  Metab Eng       Date:  2018-09-10       Impact factor: 9.783

Review 2.  Natural [4 + 2]-Cyclases.

Authors:  Byung-Sun Jeon; Shao-An Wang; Mark W Ruszczycky; Hung-Wen Liu
Journal:  Chem Rev       Date:  2016-12-01       Impact factor: 60.622

Review 3.  Genetic platforms for heterologous expression of microbial natural products.

Authors:  Jia Jia Zhang; Xiaoyu Tang; Bradley S Moore
Journal:  Nat Prod Rep       Date:  2019-06-14       Impact factor: 13.423

Review 4.  The expanding world of biosynthetic pericyclases: cooperation of experiment and theory for discovery.

Authors:  Cooper S Jamieson; Masao Ohashi; Fang Liu; Yi Tang; K N Houk
Journal:  Nat Prod Rep       Date:  2019-05-22       Impact factor: 13.423

5.  Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent.

Authors:  Rachel V K Cochrane; Randy Sanichar; Gareth R Lambkin; Béla Reiz; Wei Xu; Yi Tang; John C Vederas
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-24       Impact factor: 15.336

Review 6.  Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases.

Authors:  Carly Bond; Yi Tang; Li Li
Journal:  Fungal Genet Biol       Date:  2016-02-02       Impact factor: 3.495

7.  Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway.

Authors:  Nicholas Liu; Yiu-Sun Hung; Shu-Shan Gao; Leibniz Hang; Yi Zou; Yit-Heng Chooi; Yi Tang
Journal:  Org Lett       Date:  2017-06-13       Impact factor: 6.005

8.  Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi.

Authors:  Man-Cheng Tang; Curt R Fischer; Jason V Chari; Dan Tan; Sundari Suresh; Angela Chu; Molly Miranda; Justin Smith; Zhuan Zhang; Neil K Garg; Robert P St Onge; Yi Tang
Journal:  J Am Chem Soc       Date:  2019-05-10       Impact factor: 15.419

9.  Engineering of New Pneumocandin Side-Chain Analogues from Glarea lozoyensis by Mutasynthesis and Evaluation of Their Antifungal Activity.

Authors:  Li Chen; Yan Li; Qun Yue; Anna Loksztejn; Kenichi Yokoyama; Edd A Felix; Xingzhong Liu; Ningyan Zhang; Zhiqiang An; Gerald F Bills
Journal:  ACS Chem Biol       Date:  2016-08-10       Impact factor: 5.100

10.  Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain.

Authors:  Leibniz Hang; Man-Cheng Tang; Colin J B Harvey; Claire G Page; Jian Li; Yiu-Sun Hung; Nicholas Liu; Maureen E Hillenmeyer; Yi Tang
Journal:  Angew Chem Int Ed Engl       Date:  2017-07-05       Impact factor: 15.336
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