Wu-Chia Lo1, Po-Wen Cheng, Chi-Te Wang, Li-Jen Liao. 1. Department of Otolaryngology, Far Eastern Memorial Hospital, No. 21, Section 2, Nan-Ya South Road, Banqiao, New Taipei, Taiwan, 220.
Abstract
OBJECTIVES: To determine the efficacy of real-time elastography (RTE), compared with our previously proposed prediction model, in the detection of malignancy in cervical lymph nodes (LNs). METHODS: One hundred and thirty-one patients underwent ultrasound-guided fine needle aspiration biopsy (ultrasound FNAB) after ultrasound and RTE evaluation. The formula of the RTE scoring system was a four-point visual scale, based on a previously determined model. The formula of the prediction model was: [Formula: see text]. An extended model was constructed with four previous predictors and elasticity scores, using a logistic regression model. RESULTS: Final histology revealed 77 benign and 54 malignant LNs. In the elasticity score system, sensitivity was 66.7 %, specificity was 57.1 %, the positive predictive value (PPV) was 52.2 % and the negative predictive value (NPV) was 71.0 %. In the prediction model system, sensitivity was 79.6 %, specificity was 92.2 %, the PPV was 87.8 % and the NPV was 86.6 %. When the extended and the original model were compared, the areas under the receiver operating characteristic curve (c-statistic) was 0.94 and 0.95, respectively (P > 0.05). CONCLUSIONS: Qualitative RTE offers no additional value over conventional ultrasound in predicting malignancy in cervical LNs. KEY POINTS: • An ultrasound system can help in the assessment of cervical lymph nodes. • Grey-scale and power Doppler ultrasound remain fundamental for neck nodal evaluation. • Qualitative real-time elastography provided no additional value compared with current prediction models.
OBJECTIVES: To determine the efficacy of real-time elastography (RTE), compared with our previously proposed prediction model, in the detection of malignancy in cervical lymph nodes (LNs). METHODS: One hundred and thirty-one patients underwent ultrasound-guided fine needle aspiration biopsy (ultrasound FNAB) after ultrasound and RTE evaluation. The formula of the RTE scoring system was a four-point visual scale, based on a previously determined model. The formula of the prediction model was: [Formula: see text]. An extended model was constructed with four previous predictors and elasticity scores, using a logistic regression model. RESULTS: Final histology revealed 77 benign and 54 malignant LNs. In the elasticity score system, sensitivity was 66.7 %, specificity was 57.1 %, the positive predictive value (PPV) was 52.2 % and the negative predictive value (NPV) was 71.0 %. In the prediction model system, sensitivity was 79.6 %, specificity was 92.2 %, the PPV was 87.8 % and the NPV was 86.6 %. When the extended and the original model were compared, the areas under the receiver operating characteristic curve (c-statistic) was 0.94 and 0.95, respectively (P > 0.05). CONCLUSIONS: Qualitative RTE offers no additional value over conventional ultrasound in predicting malignancy in cervical LNs. KEY POINTS: • An ultrasound system can help in the assessment of cervical lymph nodes. • Grey-scale and power Doppler ultrasound remain fundamental for neck nodal evaluation. • Qualitative real-time elastography provided no additional value compared with current prediction models.
Authors: Kunwar S S Bhatia; Carmen C M Cho; Cina S L Tong; Edmund H Y Yuen; Anil T Ahuja Journal: Ultrasound Med Biol Date: 2011-12-16 Impact factor: 2.998
Authors: Kunwar S S Bhatia; Carmen C M Cho; Yuen-Hok Yuen; Darshana D Rasalkar; Ann D King; Anil T Ahuja Journal: Ultrasound Med Biol Date: 2010-10-15 Impact factor: 2.998
Authors: Ossama M Zakaria; Ahmed Mousa; Reema AlSadhan; Tamer A Sultan; Ahmed F Eid; Mohamed Y Daoud; Asmaa Al-Taher; Hazem M Zakaria; Krishna Swaroop; Amr M El-Gibaly; Haytham Al-Arfaj; Essam M Abdelbary Journal: Pediatr Surg Int Date: 2018-07-12 Impact factor: 1.827