Literature DB >> 23652088

Drug development for progeria yields insights into normal aging.

Kevin Jiang.   

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Year:  2013        PMID： 23652088     DOI： 10.1038/nm0513-515

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  5 in total

1.  Lamin A-dependent nuclear defects in human aging.

Authors:  Paola Scaffidi; Tom Misteli
Journal:  Science       Date:  2006-04-27       Impact factor: 47.728

2.  Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells.

Authors:  Kan Cao; John J Graziotto; Cecilia D Blair; Joseph R Mazzulli; Michael R Erdos; Dimitri Krainc; Francis S Collins
Journal:  Sci Transl Med       Date:  2011-06-29       Impact factor: 17.956

3.  Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome.

Authors:  Leslie B Gordon; Monica E Kleinman; David T Miller; Donna S Neuberg; Anita Giobbie-Hurder; Marie Gerhard-Herman; Leslie B Smoot; Catherine M Gordon; Robert Cleveland; Brian D Snyder; Brian Fligor; W Robert Bishop; Paul Statkevich; Amy Regen; Andrew Sonis; Susan Riley; Christine Ploski; Annette Correia; Nicolle Quinn; Nicole J Ullrich; Ara Nazarian; Marilyn G Liang; Susanna Y Huh; Armin Schwartzman; Mark W Kieran
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-24       Impact factor: 11.205

4.  Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

Authors:  Maria Eriksson; W Ted Brown; Leslie B Gordon; Michael W Glynn; Joel Singer; Laura Scott; Michael R Erdos; Christiane M Robbins; Tracy Y Moses; Peter Berglund; Amalia Dutra; Evgenia Pak; Sandra Durkin; Antonei B Csoka; Michael Boehnke; Thomas W Glover; Francis S Collins
Journal:  Nature       Date:  2003-04-25       Impact factor: 49.962

5.  Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria.

Authors:  Baohua Liu; Shrestha Ghosh; Xi Yang; Huiling Zheng; Xinguang Liu; Zimei Wang; Guoxiang Jin; Bojian Zheng; Brian K Kennedy; Yousin Suh; Matt Kaeberlein; Karl Tryggvason; Zhongjun Zhou
Journal:  Cell Metab       Date:  2012-12-05       Impact factor: 27.287
  5 in total

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