Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The family that eats together stays together: new p53 family transcriptional targets in autophagy.

Literature DB >> 23651851

The family that eats together stays together: new p53 family transcriptional targets in autophagy.

Abstract

Autophagy is a biological process that is crucial to maintain cellular homeostasis and is regulated by several metabolic pathways, including the p53 tumor suppressor pathway. In this issue of Genes & Development, Kenzelmann Broz and colleagues (pp. 1016-1031) show how the p53 family as a whole, including p63 and p73, collaborate in controlling autophagy to support tumor suppression.

Entities: Chemical Disease Gene

Keywords: ChIP-seq; RNA-seq; autophagy; p53; tumor suppression

Mesh：

Substances：

Year: 2013 PMID： 23651851 PMCID： PMC3656325 DOI： 10.1101/gad.219147.113

Source DB: PubMed Journal: Genes Dev ISSN： 0890-9369 Impact factor: 11.361

31 in total

Review 1. Autophagy in protists.

Authors: Michael Duszenko; Michael L Ginger; Ana Brennand; Melisa Gualdrón-López; María Isabel Colombo; Graham H Coombs; Isabelle Coppens; Bamini Jayabalasingham; Gordon Langsley; Solange Lisboa de Castro; Rubem Menna-Barreto; Jeremy C Mottram; Miguel Navarro; Daniel J Rigden; Patricia S Romano; Veronika Stoka; Boris Turk; Paul A M Michels
Journal: Autophagy Date: 2011-02-01 Impact factor: 16.016

Review 2. The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series.

Authors: Jiefei Geng; Daniel J Klionsky
Journal: EMBO Rep Date: 2008-09 Impact factor: 8.807

Review 3. Autophagy and metabolism.

Authors: Joshua D Rabinowitz; Eileen White
Journal: Science Date: 2010-12-03 Impact factor: 47.728

4. A gene signature-based approach identifies mTOR as a regulator of p73.

Authors: Jennifer M Rosenbluth; Deborah J Mays; Maria F Pino; Luo Jia Tang; Jennifer A Pietenpol
Journal: Mol Cell Biol Date: 2008-08-04 Impact factor: 4.272

5. Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

Authors: Evelyn N Kouwenhoven; Simon J van Heeringen; Juan J Tena; Martin Oti; Bas E Dutilh; M Eva Alonso; Elisa de la Calle-Mustienes; Leonie Smeenk; Tuula Rinne; Lilian Parsaulian; Emine Bolat; Rasa Jurgelenaite; Martijn A Huynen; Alexander Hoischen; Joris A Veltman; Han G Brunner; Tony Roscioli; Emily Oates; Meredith Wilson; Miguel Manzanares; José Luis Gómez-Skarmeta; Hendrik G Stunnenberg; Marion Lohrum; Hans van Bokhoven; Huiqing Zhou
Journal: PLoS Genet Date: 2010-08-19 Impact factor: 5.917

Review 6. Autophagy regulation by p53.

Authors: Maria Chiara Maiuri; Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Shoaib Ahmad Malik; Guido Kroemer
Journal: Curr Opin Cell Biol Date: 2010-01-13 Impact factor: 8.382

Review 7. Mammalian autophagy: core molecular machinery and signaling regulation.

Authors: Zhifen Yang; Daniel J Klionsky
Journal: Curr Opin Cell Biol Date: 2009-12-23 Impact factor: 8.382

Review 8. Autophagy and the integrated stress response.

Authors: Guido Kroemer; Guillermo Mariño; Beth Levine
Journal: Mol Cell Date: 2010-10-22 Impact factor: 17.970

Review 9. Metabolic regulation by p53.

Authors: Oliver D K Maddocks; Karen H Vousden
Journal: J Mol Med (Berl) Date: 2011-02-23 Impact factor: 4.599

Review 10. Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes.

Authors: Anne Simonsen; Sharon A Tooze
Journal: J Cell Biol Date: 2009-09-21 Impact factor: 10.539

13 in total

1. Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status.

Authors: Xiaoyang Li; Yuri K Peterson; Elizabeth S Inks; Richard A Himes; Jiaying Li; Yingjie Zhang; Xiujie Kong; C James Chou
Journal: J Med Chem Date: 2018-03-09 Impact factor: 7.446

2. ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer.

Authors: Marco Napoli; Avinashnarayan Venkatanarayan; Payal Raulji; Brooke A Meyers; William Norton; Lingegowda S Mangala; Anil K Sood; Cristian Rodriguez-Aguayo; Gabriel Lopez-Berestein; Harina Vin; Madeleine Duvic; Michael B Tetzlaff; Jonathan L Curry; Alain H Rook; Hussein A Abbas; Cristian Coarfa; Preethi H Gunaratne; Kenneth Y Tsai; Elsa R Flores
Journal: Cancer Cell Date: 2016-06-13 Impact factor: 31.743

Review 3. Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer.

Authors: B Liu; X Wen; Y Cheng
Journal: Cell Death Dis Date: 2013-10-31 Impact factor: 8.469

Review 4. The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy.

Authors: Marco Napoli; Elsa R Flores
Journal: Br J Cancer Date: 2016-11-24 Impact factor: 7.640