Literature DB >> 23651714

Promising results after endoscopic vacuum treatment of anastomotic leakage following resection of rectal cancer with ileostomy.

Nikolaj Nerup1, John Lykkegaard Johansen, Ghalib Ali Abod Alkhefagie, Pierre Maina, Kenneth Højsgaard Jensen.   

Abstract

INTRODUCTION: In colorectal surgery, the most feared complication is anastomotic leakage (AL), which is associated with a high morbidity and mortality. In this study, we focus on treatment of perianastomotic abscess following AL after low anterior resection (LAR) of rectal cancer. In the literature, conservative irrigation regimes are reported to perdure for months and some even years and to be associated with a poor stoma closure rate. In the present paper, we evaluated endoscopic vacuum treatment of the perianastomotic abscess.
MATERIAL AND METHODS: Patients who had LAR due to rectal cancer with total mesorectal excision (TME) performed in Slagelse and Næstved Hospitals in the 2008-2012 (1st February) period were identified in the Danish Colorectal Cancer Group database. We included patients who had AL and who did not require emergency reoperation and were treated with endoscopic vacuum in the study period. Patients who initiated treatment more than one month after the leakage were excluded. All patients had primary ileostomy.
RESULTS: A total of 13 patients were included. All patients had successful closure of the perianastomotic abscess for a median of 18 (3-40) days in a median of eight (1-18) sessions. The median length of hospital stay was 25 (7-39) days. Mortality was zero, and the stoma closure rate was 12/13 (97%).
CONCLUSION: Our data support the positive findings previously reported by other studies. Endoscopic vacuum treatment seems to be a safe approach for selected patients in the treatment of perianastomotic abscess after LAR with TME of rectal cancer. FUNDING: not relevant. TRIAL REGISTRATION: not relevant.

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Mesh:

Year:  2013        PMID: 23651714

Source DB:  PubMed          Journal:  Dan Med J        ISSN: 2245-1919            Impact factor:   1.240


  7 in total

1.  Transanal total mesorectal excision: the Slagelse experience 2013-2019.

Authors:  Sharaf Karim Perdawood; Jens Kroeigaard; Marianne Eriksen; Pauli Mortensen
Journal:  Surg Endosc       Date:  2020-02-18       Impact factor: 4.584

2.  Endoscopic Vacuum Therapy in Colorectal Surgery.

Authors:  Florian Kuehn; Florian Janisch; Frank Schwandner; Guido Alsfasser; Leif Schiffmann; Michael Gock; Ernst Klar
Journal:  J Gastrointest Surg       Date:  2015-11-23       Impact factor: 3.452

Review 3.  The use of Endo-SPONGE® in rectal anastomotic leaks: a systematic review.

Authors:  B Mahendran; B Rossi; M Coleman; S Smolarek
Journal:  Tech Coloproctol       Date:  2020-05-06       Impact factor: 3.781

Review 4.  Systematic review of endoluminal vacuum-assisted therapy as salvage treatment for rectal anastomotic leakage.

Authors:  M Shalaby; S Emile; H Elfeki; A Sakr; S D Wexner; P Sileri
Journal:  BJS Open       Date:  2018-12-26

Review 5.  Endoscopic vacuum therapy for the treatment of colorectal leaks - a systematic review and meta-analysis.

Authors:  Florian Kühn; Josefine Schardey; Ulrich Wirth; Tobias Schiergens; Alexander Crispin; Nicola Beger; Dorian Andrade; Moritz Drefs; Petra Zimmermann; Maria Burian; Joachim Andrassy; Jens Werner
Journal:  Int J Colorectal Dis       Date:  2021-11-24       Impact factor: 2.571

Review 6.  Endoluminal vacuum-assisted therapy to treat rectal anastomotic leakage: A critical analysis.

Authors:  Andrea Vignali; Paola De Nardi
Journal:  World J Gastroenterol       Date:  2022-04-14       Impact factor: 5.742

7.  Early anastomotic complications in colorectal surgery: a systematic review of techniques for endoscopic salvage.

Authors:  R E Clifford; H Fowler; N Govindarajah; D Vimalachandran; P A Sutton
Journal:  Surg Endosc       Date:  2019-01-23       Impact factor: 4.584

  7 in total

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