Literature DB >> 23651568

On skin expansion.

Djenane C Pamplona1, Raquel Q Velloso, Henrique N Radwanski.   

Abstract

This article discusses skin expansion without considering cellular growth of the skin. An in vivo analysis was carried out that involved expansion at three different sites on one patient, allowing for the observation of the relaxation process. Those measurements were used to characterize the human skin of the thorax during the surgical process of skin expansion. A comparison between the in vivo results and the numerical finite elements model of the expansion was used to identify the material elastic parameters of the skin of the thorax of that patient. Delfino's constitutive equation was chosen to model the in vivo results. The skin is considered to be an isotropic, homogeneous, hyperelastic, and incompressible membrane. When the skin is extended, such as with expanders, the collagen fibers are also extended and cause stiffening in the skin, which results in increasing resistance to expansion or further stretching. We observed this phenomenon as an increase in the parameters as subsequent expansions continued. The number and shape of the skin expanders used in expansions were also studied, both mathematically and experimentally. The choice of the site where the expansion should be performed is discussed to enlighten problems that can lead to frustrated skin expansions. These results are very encouraging and provide insight into our understanding of the behavior of stretched skin by expansion. To our knowledge, this study has provided results that considerably improve our understanding of the behavior of human skin under expansion.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Biomembranes; Characterization of human skin; Constitutive equation; Elastic foundation; Finite elements; Skin expanders; Skin expansion

Mesh:

Year:  2013        PMID: 23651568     DOI: 10.1016/j.jmbbm.2013.03.023

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  8 in total

1.  Improving tissue expansion protocols through computational modeling.

Authors:  Taeksang Lee; Elbert E Vaca; Joanna K Ledwon; Hanah Bae; Jolanta M Topczewska; Sergey Y Turin; Ellen Kuhl; Arun K Gosain; Adrian Buganza Tepole
Journal:  J Mech Behav Biomed Mater       Date:  2018-03-29

2.  Multi-view stereo analysis reveals anisotropy of prestrain, deformation, and growth in living skin.

Authors:  Adrián Buganza Tepole; Michael Gart; Chad A Purnell; Arun K Gosain; Ellen Kuhl
Journal:  Biomech Model Mechanobiol       Date:  2015-01-30

3.  Growth on demand: reviewing the mechanobiology of stretched skin.

Authors:  Alexander M Zöllner; Maria A Holland; Kord S Honda; Arun K Gosain; Ellen Kuhl
Journal:  J Mech Behav Biomed Mater       Date:  2013-04-03

4.  Bayesian calibration of a computational model of tissue expansion based on a porcine animal model.

Authors:  Tianhong Han; Taeksang Lee; Joanna Ledwon; Elbert Vaca; Sergey Turin; Aaron Kearney; Arun K Gosain; Adrian B Tepole
Journal:  Acta Biomater       Date:  2021-10-08       Impact factor: 8.947

5.  The Incompatibility of Living Systems: Characterizing Growth-Induced Incompatibilities in Expanded Skin.

Authors:  Adrian Buganza Tepole; Michael Gart; Chad A Purnell; Arun K Gosain; Ellen Kuhl
Journal:  Ann Biomed Eng       Date:  2015-09-28       Impact factor: 3.934

6.  Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery.

Authors:  Adrián Buganza Tepole; Arun K Gosain; Ellen Kuhl
Journal:  Comput Struct       Date:  2014-09-01       Impact factor: 4.578

7.  Histological changes of immediate skin expansion of the distal limb of rats.

Authors:  Ahmed Khalaf Ali; Adamu Abdul Abubakar; Ubedullah Kaka; Zamri Radzi; Nurul Hayah Khairuddin; Md Sabri Mohd Yusoff; Mohamad Yusof Loqman
Journal:  Vet World       Date:  2018-12-20

8.  A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration.

Authors:  Poh-Ching Tan; Pei-Chuan Chao; Chen Cheng; Chu-Hsin Chen; Ru-Lin Huang; Shuang-Bai Zhou; Yun Xie; Qing-Feng Li
Journal:  Stem Cell Res Ther       Date:  2021-04-15       Impact factor: 6.832

  8 in total

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