Literature DB >> 23649200

Two new diterpenoids from cell cultures of Salvia miltiorrhiza.

De-Wu Zhang1, Xiao Liu, Dan Xie, Ridao Chen, Xiao-Yu Tao, Jian-Hua Zou, Jungui Dai.   

Abstract

A new spiroketallactone, epi-danshenspiroketallactone A (1) and a new C18-norditerpenoid, normiltioane (2) along with 21 known compounds, were isolated from cell cultures of Salvia miltiorrhiza. Their structures were elucidated on the basis of extensive spectroscopic analyses. In the in vitro assays, the compounds 9-11, 21-23 exhibited the significant antitumor activity with the IC(50) ranges of 1.0-8.3 µM.

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Year:  2013        PMID: 23649200     DOI: 10.1248/cpb.c12-00987

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

1.  New diterpenoid quinones derived from Salvia miltiorrhiza and their cytotoxic and neuroprotective activities.

Authors:  Zhao-Kun Yin; Zi-Ming Feng; Jian-Shuang Jiang; Xu Zhang; Pei-Cheng Zhang; Ya-Nan Yang
Journal:  RSC Adv       Date:  2020-04-08       Impact factor: 3.361

2.  Diterpenoids from the Roots of Salvia yunnanensis.

Authors:  Fan Xia; Chun-Yan Wu; Xing-Wei Yang; Xian Li; Gang Xu
Journal:  Nat Prod Bioprospect       Date:  2015-12-14

3.  Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components.

Authors:  Sha Li; Ning Wang; Ming Hong; Hor-Yue Tan; Guofeng Pan; Yibin Feng
Journal:  Molecules       Date:  2018-02-07       Impact factor: 4.411

  3 in total

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