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Literature DB >> 23646068

Cytoplasmic dynein: tension generation on microtubules and the nucleus.

Nandini Shekhar¹, Jun Wu, Richard B Dickinson, Tanmay P Lele.

Abstract

Cytoplasmic dynein is a microtubule dependent motor protein that is central to vesicle transport, cell division and organelle positioning. Recent studies suggest that dynein can generate significant pulling forces on intracellular structures as it motors along microtubules. In this review, we discuss how dynein-generated pulling forces position the nucleus and the centrosome.

Entities: CellLine Chemical Disease Gene Species

Keywords: Centrosome Centering; Cytoplasmic Dynein; Force Generation; Nuclear Positioning

Year: 2013 PMID： 23646068 PMCID： PMC3640586 DOI： 10.1007/s12195-012-0257-4

Source DB: PubMed Journal: Cell Mol Bioeng ISSN： 1865-5025 Impact factor: 2.321

63 in total

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Journal: Nature Date: 2003-02-13 Impact factor: 49.962

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Authors: Jennifer A Johnston; Michelle E Illing; Ron R Kopito
Journal: Cell Motil Cytoskeleton Date: 2002-09

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Authors: Roop Mallik; Brian C Carter; Stephanie A Lex; Stephen J King; Steven P Gross
Journal: Nature Date: 2004-02-12 Impact factor: 49.962

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Journal: Nature Date: 1991-08-15 Impact factor: 49.962

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Authors: Juehua Yu; Kai Lei; Min Zhou; Cheryl M Craft; Gezhi Xu; Tian Xu; Yuan Zhuang; Rener Xu; Min Han
Journal: Hum Mol Genet Date: 2010-12-21 Impact factor: 6.150

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Authors: Janice A Fischer; Shelley Acosta; Andrew Kenny; Courtney Cater; Christina Robinson; Jay Hook
Journal: Genetics Date: 2004-11 Impact factor: 4.562

6 in total

1. Circovirus transport proceeds via direct interaction of the cytoplasmic dynein IC1 subunit with the viral capsid protein.

Authors: Jingjing Cao; Cui Lin; Huijuan Wang; Lun Wang; Niu Zhou; Yulan Jin; Min Liao; Jiyong Zhou
Journal: J Virol Date: 2014-12-24 Impact factor: 5.103

2. Analysis of microtubule growth dynamics arising from altered actin network structure and contractility in breast tumor cells.

Authors: Eleanor C Ory; Lekhana Bhandary; Amanda E Boggs; Kristi R Chakrabarti; Joshua Parker; Wolfgang Losert; Stuart S Martin
Journal: Phys Biol Date: 2017-04-20 Impact factor: 2.583