Literature DB >> 23646064

Reactions, beliefs and concerns associated with providing hair specimens for medical research among a South African sample: a qualitative approach.

Bronwyne Coetzee1, Ashraf Kagee, Mark Tomlinson, Louise Warnich, Ogechi Ikediobi.   

Abstract

In order to optimize treatment outcome among antiretroviral therapy users, there is a strong imperative to engage in continued monitoring and maintenance of therapeutic drug levels in patients. The aim of this study was to document the perspectives, beliefs, and concerns of South African antiretroviral therapy users providing hair specimens to determine antiretroviral drug levels. Twenty-one women living with HIV were recruited from a community health center in the Western Cape. Interviews were recorded and transcribed, and analyzed using Atlas.ti version 6. Although participants identified several cultural beliefs influencing their decision to provide hair specimens for drug level measurement, nearly all agreed that they would be willing to do so if provided with enough information by the researcher.

Entities:  

Keywords:  adherence; antiretroviral therapy; barriers; culture; drug testing; hair

Year:  2012        PMID: 23646064      PMCID: PMC3640774          DOI: 10.2217/fvl.12.100

Source DB:  PubMed          Journal:  Future Virol        ISSN: 1746-0794            Impact factor:   1.831


  21 in total

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Authors:  T Grzybowski
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Review 2.  Practicing participatory research in American Indian communities.

Authors:  S M Davis; R Reid
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Review 3.  Measuring adherence to antiretroviral medications in clinical trials.

Authors:  L G Miller; R D Hays
Journal:  HIV Clin Trials       Date:  2000 Jul-Aug

Review 4.  Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management.

Authors:  Jane M Simoni; Ann E Kurth; Cynthia R Pearson; David W Pantalone; Joseph O Merrill; Pamela A Frick
Journal:  AIDS Behav       Date:  2006-05

5.  The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings.

Authors:  Charles F Gilks; Siobhan Crowley; René Ekpini; Sandy Gove; Jos Perriens; Yves Souteyrand; Don Sutherland; Marco Vitoria; Teguest Guerma; Kevin De Cock
Journal:  Lancet       Date:  2006-08-05       Impact factor: 79.321

6.  Treatment adherence following national antiretroviral rollout in South Africa.

Authors:  Alta C Van Dyk
Journal:  Afr J AIDS Res       Date:  2010-09       Impact factor: 1.300

Review 7.  Ethical aspects of genome diversity research: genome research into cultural diversity or cultural diversity in genome research?

Authors:  Ilhan Ilkilic; Norbert W Paul
Journal:  Med Health Care Philos       Date:  2008-07-01

Review 8.  Pharmacogenetics of antiretrovirals.

Authors:  Valerio Tozzi
Journal:  Antiviral Res       Date:  2009-09-08       Impact factor: 5.970

9.  Protease inhibitor levels in hair strongly predict virologic response to treatment.

Authors:  Monica Gandhi; Niloufar Ameli; Peter Bacchetti; Stephen J Gange; Kathryn Anastos; Alexandra Levine; Charles L Hyman; Mardge Cohen; Mary Young; Yong Huang; Ruth M Greenblatt
Journal:  AIDS       Date:  2009-02-20       Impact factor: 4.177

10.  Clinical prognostic value of RNA viral load and CD4 cell counts during untreated HIV-1 infection--a quantitative review.

Authors:  Eline L Korenromp; Brian G Williams; George P Schmid; Christopher Dye
Journal:  PLoS One       Date:  2009-06-17       Impact factor: 3.240

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  15 in total

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Authors:  Monica Gandhi; David V Glidden; Albert Liu; Peter L Anderson; Howard Horng; Patricia Defechereux; Juan V Guanira; Beatriz Grinsztejn; Suwat Chariyalertsak; Linda-Gail Bekker; Robert M Grant
Journal:  J Infect Dis       Date:  2015-04-20       Impact factor: 5.226

2.  Willingness to Donate Hair Samples for Research Among People Living with HIV/AIDS Attending a Tertiary Health Facility in Ibadan, Nigeria.

Authors:  Jacinta N Nwogu; Chinedum P Babalola; Samuel O Ngene; Babafemi O Taiwo; Baiba Berzins; Monica Gandhi
Journal:  AIDS Res Hum Retroviruses       Date:  2019-05-29       Impact factor: 2.205

3.  Defining a Cutoff for Atazanavir in Hair Samples Associated With Virological Failure Among Adolescents Failing Second-Line Antiretroviral Treatment.

Authors:  Tariro D Chawana; Monica Gandhi; Kusum Nathoo; Bernard Ngara; Alexander Louie; Howard Horng; David Katzenstein; John Metcalfe; Charles F B Nhachi
Journal:  J Acquir Immune Defic Syndr       Date:  2017-09-01       Impact factor: 3.731

4.  Relation Between Religious Perspectives and Views on Sickle Cell Disease Research and Associated Public Health Interventions in Ghana.

Authors:  Jemima A Dennis-Antwi; Kwaku Ohene-Frempong; Kofi A Anie; Helen Dzikunu; Veronica A Agyare; Richard Okyere Boadu; Joseph Sarfo Antwi; Mabel K Asafo; Oboshie Anim-Boamah; Augustine K Asubonteng; Solomon Agyei; Ambroise Wonkam; Marsha J Treadwell
Journal:  J Genet Couns       Date:  2018-09-01       Impact factor: 2.537

5.  Using Lopinavir Concentrations in Hair Samples to Assess Treatment Outcomes on Second-Line Regimens Among Asian Children.

Authors:  Wasana Prasitsuebsai; Stephen J Kerr; Khanh Huu Truong; Jintanat Ananworanich; Viet Chau Do; Lam Van Nguyen; Nia Kurniati; Pope Kosalaraksa; Tavitiya Sudjaritruk; Kulkanya Chokephaibulkit; Narukjaporn Thammajaruk; Thida Singtoroj; Sirinya Teeraananchai; Howard Horng; Peter Bacchetti; Monica Gandhi; Annette H Sohn
Journal:  AIDS Res Hum Retroviruses       Date:  2015-08-26       Impact factor: 2.205

6.  CYP2B6*6 and CYP2B6*18 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women.

Authors:  Carola R Röhrich; Britt I Drögemöller; Ogechi Ikediobi; Lize van der Merwe; Nelis Grobbelaar; Galen E B Wright; Nathaniel McGregor; Louise Warnich
Journal:  AIDS Res Hum Retroviruses       Date:  2016-01-29       Impact factor: 2.205

7.  Willingness to provide a hair sample for drug testing among electronic dance music party attendees.

Authors:  Joseph J Palamar; Alberto Salomone; Charles M Cleland; Scott Sherman
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8.  Ethical and legal implications of whole genome and whole exome sequencing in African populations.

Authors:  Galen E B Wright; Pieter G J Koornhof; Adebowale A Adeyemo; Nicki Tiffin
Journal:  BMC Med Ethics       Date:  2013-05-28       Impact factor: 2.652

9.  High Acceptability of Donating Hair and Other Biological Samples for Research Among People Living with HIV in an Outpatient Clinic in Lagos, Nigeria.

Authors:  Ebiere C Herbertson; Cecile D Lahiri; Jacinta N Nwogu; Rebecca O Soremekun; Olubusola A Olugbake; Oliver C Ezechi; Alani S Akanmu; Monica Gandhi
Journal:  AIDS Res Hum Retroviruses       Date:  2021-04-15       Impact factor: 1.723

10.  Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP).

Authors:  Albert Y Liu; Qiyun Yang; Yong Huang; Peter Bacchetti; Peter L Anderson; Chengshi Jin; Kathy Goggin; Kristefer Stojanovski; Robert Grant; Susan P Buchbinder; Ruth M Greenblatt; Monica Gandhi
Journal:  PLoS One       Date:  2014-01-08       Impact factor: 3.240

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