Literature DB >> 23645700

Hyperphosphatemic tumoral calcinosis.

Saumyaranjan Mallick1, Zohra Ahmad, Arun K Gupta, Sandeep R Mathur.   

Abstract

Tumoral calcinosis (TC) is a rare locally aggressive lesion characterised by extra-articular soft tissue deposition of the calcium phosphate around large joints. The exact aetiology is not known. A 19-year-old boy presented with a painful progressive swelling around the bilateral elbow and left hip joints over a 6-month duration. Routine laboratory results showed a normal haemogram, and normal calcium and high phosphate levels. Imaging showed a soft tissue calcified mass around these joints. The cut surface of the excised mass showed myxoid material with areas of calcification. On microscopy, there were typical features of TC. Our case is being presented due to the rarity of the entity and the peculiar dual energy CT (DECT) finding which are being described for the first time in this pathology.

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Year:  2013        PMID: 23645700      PMCID: PMC3669765          DOI: 10.1136/bcr-2013-008728

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

Review 1.  Miscellaneous non-inflammatory musculoskeletal conditions. Hyperphosphatemic familial tumoral calcinosis (FGF23, GALNT3 and αKlotho).

Authors:  Emily G Farrow; Erik A Imel; Kenneth E White
Journal:  Best Pract Res Clin Rheumatol       Date:  2011-10       Impact factor: 4.098

2.  Heterotopic calcification, hyperphosphatemia and angioid streaks of the retina.

Authors:  J J MCPHAUL; F L ENGEL
Journal:  Am J Med       Date:  1961-09       Impact factor: 4.965

3.  Tumoral calcinosis revisited--common and uncommon features. Report of ten cases and review.

Authors:  A Metzker; B Eisenstein; J Oren; R Samuel
Journal:  Eur J Pediatr       Date:  1988-02       Impact factor: 3.183

4.  Tumoral calcinosis--or is it? A case report and review.

Authors:  Warren C Hammert; Leroy R Lindsay
Journal:  Hand (N Y)       Date:  2008-09-19

Review 5.  Cutaneous deposition diseases. Part II.

Authors:  D M Touart; P Sau
Journal:  J Am Acad Dermatol       Date:  1998-10       Impact factor: 11.527

6.  Normophosphatemic type tumoral calcinosis associated with chronic recurrent multifocal osteomyelitis: a case report.

Authors:  Halil Yalçın Yüksel; Serdar Yılmaz; Mihriban Gürbüzel
Journal:  Acta Orthop Traumatol Turc       Date:  2011       Impact factor: 1.511

Review 7.  Proposal for a pathogenesis-based classification of tumoral calcinosis.

Authors:  D Smack; S A Norton; J E Fitzpatrick
Journal:  Int J Dermatol       Date:  1996-04       Impact factor: 2.736

8.  Aggressive tumoral calcinosis in an infant thoracotomy scar.

Authors:  Jakub Kadlec; Bohumil Hucin; Tomas Tlaskal; Stephen Westaby
Journal:  Interact Cardiovasc Thorac Surg       Date:  2010-09-21

9.  Tumoral calcinosis, diaphysitis, and hyperphosphatemia.

Authors:  E Clarke; L E Swischuk; C K Hayden
Journal:  Radiology       Date:  1984-06       Impact factor: 11.105

10.  Normophosphatemic familial tumoral calcinosis is caused by deleterious mutations in SAMD9, encoding a TNF-alpha responsive protein.

Authors:  Ilana Chefetz; Danny Ben Amitai; Sarah Browning; Karl Skorecki; Noam Adir; Mark G Thomas; Larissa Kogleck; Orit Topaz; Margarita Indelman; Jouni Uitto; Gabriele Richard; Neil Bradman; Eli Sprecher
Journal:  J Invest Dermatol       Date:  2007-12-20       Impact factor: 8.551

  10 in total

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