| Literature DB >> 2364310 |
C C Vassella1, A L de Weck, B M Stadler.
Abstract
A simple method is described which enables measurement of anti-IgE antibodies in free form as well as in immune complexes of IgE and anti-IgE. Anti-IgE antibodies were purified from serum of one selected blood donor with highly elevated levels of such autoantibodies. These purified anti-IgE auto-antibodies inhibited the measurement of myeloma IgE. Purification also revealed that 98% of the subject's serum IgE was masked by anti-IgE auto-antibodies. Our data suggest that IgE determinations in sera containing anti-IgE antibodies might be underestimated.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2364310 DOI： 10.1111/j.1365-2222.1990.tb02687.x
Source DB: PubMed Journal: Clin Exp Allergy ISSN： 0954-7894 Impact factor: 5.018