| Literature DB >> 23642454 |
Muhammad Saleem1, Muhammad Imran Tousif, Naheed Riaz, Ishtiaq Ahmed, Barbara Schulz, Muhammad Ashraf, Rumana Nasar, Gennaro Pescitelli, Hidayat Hussain, Abdul Jabbar, Nusrat Shafiq, Karsten Krohn.
Abstract
An antibiotic polyketide, Cryptosporioptide (1) was isolated from the culture extract of the endophytic fungus Cryptosporiopsis sp. The structure of Cryptosporioptide has been established with the help of 1D ((1)H, (13)C), 2D NMR (HSQC, HMBC, COSY, NOESY) techniques and mass spectrometry (FABMS, HRFABMS). The absolute configuration was established by means of electronic circular dichroism (ECD). Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities.Entities:
Keywords: Anti-Bacillus megaterium; Cryptosporiopsis sp.; Endophytic fungus; Lipoxygenase inhibition; Novel polyketide; TDDFT CD calculations
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Year: 2013 PMID： 23642454 DOI： 10.1016/j.phytochem.2013.03.018
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072