| Literature DB >> 23642356 |
Abstract
Mechanisms underlying alternative modes of symmetric versus asymmetric stem cell fates are not well understood. In this issue of Cell Stem Cell, Bu et al. (2013) find that miR-34a acts as a toggle switch for Notch signaling that dictates binary symmetric and asymmetric fates in colon cancer stem cells.Entities:
Year: 2013 PMID: 23642356 DOI: 10.1016/j.stem.2013.04.018
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633