Literature DB >> 23642356

miR-34a sets the "sweet spot" for notch in colorectal cancer stem cells.

Douglas J Winton1.   

Abstract

Mechanisms underlying alternative modes of symmetric versus asymmetric stem cell fates are not well understood. In this issue of Cell Stem Cell, Bu et al. (2013) find that miR-34a acts as a toggle switch for Notch signaling that dictates binary symmetric and asymmetric fates in colon cancer stem cells.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Year:  2013        PMID: 23642356     DOI: 10.1016/j.stem.2013.04.018

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  7 in total

1.  Cancer-associated fibroblasts promote stem cell-like properties of hepatocellular carcinoma cells through IL-6/STAT3/Notch signaling.

Authors:  Si Xiong; Ronghua Wang; Qian Chen; Jing Luo; Jinlin Wang; Zhenxiong Zhao; Yawen Li; Yun Wang; Xiju Wang; Bin Cheng
Journal:  Am J Cancer Res       Date:  2018-02-01       Impact factor: 6.166

Review 2.  MicroRNAs as diagnostic and prognostic biomarkers in colorectal cancer.

Authors:  Rui Yi; Yao Li; Fei-Liang Wang; Gang Miao; Ruo-Mei Qi; Yan-Yang Zhao
Journal:  World J Gastrointest Oncol       Date:  2016-04-15

3.  MiR-34a inhibits migration and invasion by regulating the SIRT1/p53 pathway in human SW480 cells.

Authors:  Mingguang Lai; Gang Du; Ruiyue Shi; Jun Yao; Genhua Yang; Yue Wei; Dingguo Zhang; Zhenglei Xu; Ru Zhang; Yingxue Li; Zicheng Li; Lisheng Wang
Journal:  Mol Med Rep       Date:  2015-01-12       Impact factor: 2.952

Review 4.  An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities That Drive Colon Cancer Development.

Authors:  Bruce M Boman; Jeremy Z Fields
Journal:  Front Oncol       Date:  2013-11-07       Impact factor: 6.244

Review 5.  Mir-34: a new weapon against cancer?

Authors:  Gabriella Misso; Maria Teresa Di Martino; Giuseppe De Rosa; Ammad Ahmad Farooqi; Angela Lombardi; Virginia Campani; Mayra Rachele Zarone; Annamaria Gullà; Pierosandro Tagliaferri; Pierfrancesco Tassone; Michele Caraglia
Journal:  Mol Ther Nucleic Acids       Date:  2014-09-23       Impact factor: 10.183

6.  Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells.

Authors:  Ronghua Wang; Qian Sun; Peng Wang; Man Liu; Si Xiong; Jing Luo; Hai Huang; Qiang Du; David A Geller; Bin Cheng
Journal:  Oncotarget       Date:  2016-02-02

7.  3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.

Authors:  Junli Chen; Hui Chang; Xiaoli Peng; Yeyun Gu; Long Yi; Qianyong Zhang; Jundong Zhu; Mantian Mi
Journal:  Sci Rep       Date:  2016-06-27       Impact factor: 4.379

  7 in total

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